BCL9 Antibody, Biotin Conjugated

  • Catalog number
    bs-12393R-Biotin
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    BCL9 Polyclonal Antibody, Biotin Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Biotin
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    BCL9
  • Specificity
    This is a highly specific antibody against BCL9.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human BCL9
  • Gene ID number
    101060700
  • Tested applications
    WB, IHC-P
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Bcl-9L is a 1,499 amino acid protein that localizes to the nucleus and contains a specialized C-terminal domain that is important for its overall activity. Expressed in breast tissue, as well as in eye, lung, prostate and various carcinomas, Bcl-9L functions as a transcriptional activator that forms a complex with Parafibromin and β-catenin and is thought promote the transcriptional activity of Parafibromin and enhance the neoplastic transforming activity of β-catenin. Bcl-9L exists as multiple alternatively spliced isoforms and is thought to be involved in tumorigenesis, possibly playing a role in tumor transformation and metastasis. The gene encoding Bcl-9L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    N/A
  • Synonyms
    B-cell CLL/lymphoma 9; BCL 9; BCL-9; DLNB11; Legless homolog; B-cell CLL/lymphoma 9-like; LGS; BCL9_HUMAN.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Additional conjugation
    Biotinylated
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    BCL9, BCL9L
  • Short name
    Anti-BCL9
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Biotin
  • Alternative name
    Anti-BCL9 PAb Biotin
  • Alternative technique
    antibodies
  • Alternative to gene target
    B-cell CLL/lymphoma 9, LGS, BCL9 and IDBG-101829 and ENSG00000116128 and 607, beta-catenin binding, nuclei, Bcl9 and IDBG-176803 and ENSMUSG00000038256 and 77578, BCL9 and IDBG-633778 and ENSBTAG00000002422 and 788729
Gene info
  • Identity
  • Gene
  • Long gene name
    BCL9 transcription coactivator
  • Synonyms gene name
    • B cell CLL/lymphoma 9
    • BCL9, transcription coactivator
  • GenBank acession
  • Locus
  • Discovery year
    1997-07-01
  • Entrez gene record
    607
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Wnt enhanceosome complex
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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