anti-GLE1 Antibody

• Catalog number
  26-893
• Price
  Please ask
• Size
  50 ug

• Gene info
  GLE1 is a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Gene names
  GLE1, GLE1L, hGLE1, LCCS, LCCS1
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GLE1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  GLE1 antibody can be used for detection of GLE1 by ELISA at 1:1562500. GLE1 antibody can be used for detection of GLE1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store GLE1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  4557627
• Ncbi nr
  NP_001490
• KDa
  75 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  2733
• GENE symbol
  GLE1
• Antigene name
  GLE1 RNA export mediator
• Source
  Homo sapiens
• Protein nr
  Q53GS7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GLE1  
• Gene symbol
  GLE1
• Short name
  anti-GLE1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toGLE1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4315
• Gene
  GLE1
• Long gene name
  GLE1 RNA export mediator
• Synonyms gene
  • GLE1L
  • LCCS1
• Synonyms gene name
  • GLE1 (yeast homolog)-like, RNA export mediator
  • GLE1 RNA export mediator-like (yeast)
  • GLE1 RNA export mediator (yeast)
  • lethal congenital contracture syndrome 1
  • GLE1 RNA export mediator homolog (yeast)
  • GLE1, RNA export mediator
• Synonyms
  • hGLE1
• GenBank acession
  • AF058922
• Locus
  9q34.11
• Discovery year
  1998-06-18
• Entrez gene record
  2733
• Pubmed identfication
  • 9618489
  • 18204449
• RefSeq identity
  • NM_001003722
• Classification
  • Nucleoporins
• VEGA ID
  OTTHUMG00000020749
• Locus Specific Databases
  • LRG_484

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products