Phospho-AMPKα1 (Ser496) Antibody

  • Catalog number
    A1247-100
  • Price
    Please ask
  • Size
    100 µl
  • Antibody Target
    PRKAA1
  • Target Alternative Name
    PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; H mgCR kinase; Tau-protein kinase PRKAA1
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, mouse , rat
  • Immunogen Sequence
    Synthesized peptide derived from human AMPKα1 around the phosphorylation site of S496 (420-500aa)
  • Accession
    Q13131
  • Gene Id
    5562
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
  • Purification
    Affinity-chromatography using epitope-specific immunogen
  • Application
    WB, ELISA, IHC
  • Positive Control
    WB: HeLa cell lysate
  • Application And Usages
    WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000
  • Description
    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans
  • Handling
    The antibody solution should be gently mixed before use
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    PRKAA2
  • Short name
    Phospho-AMPKα1 (Ser496) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    phosphorilated-AMPKα1 (Ser496) (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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