EMD Polyclonal Antibody

• Catalog number
  CAC07852
• Price
  Please ask
• Size
  50 μg

• Other name
  Emerin,EMD,EDMD,STA
• Immunogen
  Recombinant Human Emerin protein (1-222AA)
• Verified reactivity
  Human, Mouse
• Verified applications
  ELISA,WB,IHC,IF,IP. Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:200,IP:1:200-1:2000
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  P50402
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  EMD  
• Gene symbol
  EMD
• Short name
  EMD Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  EMD polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:3331
• Gene
  EMD
• Long gene name
  emerin
• Synonyms gene name
  • Emery-Dreifuss muscular dystrophy
• Synonyms
  • STA
  • LEMD5
• Synonyms name
  • LEM domain containing 5
• GenBank acession
  • X82434
• Locus
  Xq28
• Discovery year
  2001-06-22
• Entrez gene record
  2010
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000033186
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • UMD Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • Global Variome shared LOVD
  • LRG_745

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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