HC-II (D68) polyclonal antibody

Alternative Name

Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1; SERPIND1; HCF2
Immunogen

Synthetic peptide, corresponding to amino acids 41-90 of Human HC-II.
Swiss Prot

P05546
Reactivity

Human,Mouse,Rat
Applications

IHC
Application_all

IHC: 1:50~1:200
Product

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage Stability

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity

HC-II (D68) polyclonal antibody detects endogenous levels of HC-II protein.
Usage

NA
BiowMW

~ 57 kDa
Note

For research use only, not for use in diagnostic procedure.
Properties

If you buy Antibodies supplied by Bioworld they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation

anticorps

Gene target

HC-II D68
Gene symbol

SERPIND1, CLTC, SRRD, CRABP2, SPINK2, MGST2, IBSP, APOL2, MGAT2, P4HA2
Short name

HC-II (D68) polyclonal antibody
Technique

Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Rabbit
Alternative name

HC-II (D68) polyclonal (antibody to-)
Alternative technique

polyclonals, antibodies

Identity

HGNC:4838
Gene

SERPIND1
Long gene name

serpin family D member 1
Synonyms gene
- HCF2
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1
- serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Synonyms
- HC-II
- HLS2
- HC2
- D22S673
Synonyms name
- heparin cofactor II
- heparin cofactor 2
GenBank acession
- M12849
Locus

22q11.21
Discovery year

1988-05-31
Entrez gene record

3053
Pubmed identfication
- 1671335
- 24172014
RefSeq identity
- NM_000185
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000150755
Locus Specific Databases
- LRG_594

Identity

HGNC:2092
Gene

CLTC
Long gene name

clathrin heavy chain
Synonyms gene
- CLTCL2
Synonyms gene name
- clathrin, heavy polypeptide (Hc)
- clathrin, heavy chain
- clathrin, heavy polypeptide-like 2
- clathrin, heavy chain (Hc)
Synonyms
- Hc
GenBank acession
- X55878
Locus

17q23.1
Discovery year

1990-10-16
Entrez gene record

1213
Pubmed identfication
- 1765375
- 7584026
RefSeq identity
- NM_004859
Classification
- Clathrin subunits
VEGA ID

OTTHUMG00000134279

Identity

HGNC:11245
Gene

SPINK2
Long gene name

serine peptidase inhibitor Kazal type 2
Synonyms gene name
- serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
Synonyms
- HUSI-II
Synonyms name
- acrosin-trypsin inhibitor
GenBank acession
- BC022514
Locus

4q12
Discovery year

1993-12-01
Entrez gene record

6691
Pubmed identfication
- 8428671
RefSeq identity
- NM_021114
Classification
- Serine peptidase inhibitors, Kazal type
VEGA ID

OTTHUMG00000128769

Identity

HGNC:7045
Gene

MGAT2
Long gene name

alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Synonyms gene name
- mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Synonyms
- GNT-II
GenBank acession
- U15128
Locus

14q21.3
Discovery year

1993-02-16
Entrez gene record

4247
Pubmed identfication
- 7635144
RefSeq identity
- NM_002408
Classification
- Mannosyl-glycoprotein N-acetylglucosaminyltransferases
VEGA ID

OTTHUMG00000140271
Locus Specific Databases
- Congenital Disorder of Glycosylation pages

Identity

HGNC:8547
Gene

P4HA2
Long gene name

prolyl 4-hydroxylase subunit alpha 2
Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
- prolyl 4-hydroxylase, alpha polypeptide II
Synonyms
- C-P4Halpha(II)
Synonyms name
- 4-PH alpha 2
- collagen prolyl 4-hydroxylase alpha(II)
GenBank acession
- U90441
Locus

5q31.1
Discovery year

1999-02-23
Entrez gene record

8974
Pubmed identfication
- 9211872
- 9149945
RefSeq identity
- NM_004199
Classification
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000059647

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data