CD47 Antibody

• Catalog number
  PA2223
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CD47
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human CD47(308-323aa EPLNAFKESKGMMNDE), identical to the related rat sequence.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the CD47 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CD47 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  CD47, also known as IAP or MER6, is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 gene belongs to the immunoglobulin superfamily. This gene is mapped to 3q13.12. CD47 gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
• Related articles
  1. Bras, M., Yuste, V. J., Roue, G., Barbier, S., Sancho, P., Virely, C., Rubio, M., Baudet, S., Esquerda, J. E., Merle-Beral, H., Sarfati, M., Susin, S. A. Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. Molec. Cell. Biol. 27: 7073-7088, 2007. 2. Han, X., Sterling, H., Chen, Y., Saginario, C., Brown, E. J., Frazier, W. A., Lindberg, F. P., Vignery, A. CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation. J. Biol. Chem. 275: 37984-37992, 2000. 3. Oldenborg, P.-A., Zheleznyak, A., Fang, Y.-F., Lagenaur, C. F., Gresham, H. D., Lindberg, F. P. Role of CD47 as a marker of self on red blood cells. Science 288: 2051-2054, 2000.
• Gene Name
  CD47
• Protein Name
  Leukocyte surface antigen CD47
• Gene Full Name
  CD47 molecule
• Synonyms
  Antigenic surface determinant protein OA3 antibody|CD 47 antibody|CD47 antibody|Cd47 antibody|CD47 antigen(Rh-related antigen, integrin-associated signal transducer) antibody|CD47 antigen antibody|CD47 glycoprotein antibody|CD47 molecule antibody|CD47_HUMAN antibody|IAP antibody|Integrin Associated Protein antibody|Integrin associated signal transducer antibody|Integrin-associated protein antibody|Leukocyte surface antigen CD47 antibody|MER 6 antibody|MER6 antibody|OA 3 antibody|OA3 antibody|OTTHUMP00000041152 antibody|OTTHUMP00000041153 antibody|Protein MER6 antibody|Rh related antigen antibody
• Uniprot ID
  Q08722
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD47  
• Gene symbol
  CD47
• Short name
  CD47 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  CD47 molecule (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  CD47 molecule, IAP and MER6 and OA3, CD47 and IDBG-48744 and ENSG00000196776 and 961, thrombospondin receptor activity, Plasma membranes, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661

Gene info

• Identity
  HGNC:1682
• Gene
  CD47
• Long gene name
  CD47 molecule
• Synonyms gene
  • MER6
• Synonyms gene name
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
• Synonyms
  • IAP
  • OA3
• Synonyms name
  • antigen identified by monoclonal antibody 1D8
  • antigenic surface determinant protein OA3
  • integrin associated protein
  • Rh-related antigen
  • leukocyte surface antigen CD47
  • CD47 glycoprotein
• Locus
  3q13.12
• Discovery year
  1994-12-12
• Entrez gene record
  961
• Pubmed identfication
  • 8294396
  • 2277087
• RefSeq identity
  • NM_001777
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000044216

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products