SMAD1 Antibody
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Catalog numberF47786-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSMAD1
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000
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NotesTitration of the SMAD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis SMAD1 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ15797
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PurityAntigen affinity
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DescriptionThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
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ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this SMAD1 antibody.
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StorageAliquot the SMAD1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSMAD1-AS2, SMAD1-AS1, SMAD1, GARS1
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Short nameAnti-SMAD1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to SMAD1
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Alternative techniqueantibodies
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Alternative to gene targetSMAD family member 1, BSP-1 and BSP1 and JV4-1 and JV41 and MADH1 and MADR1, SMAD1 and IDBG-39936 and ENSG00000170365 and 4086, transforming growth factor beta receptor, nuclei, Smad1 and IDBG-170516 and ENSMUSG00000031681 and 17125, SMAD1 and IDBG-629431 and ENSBTAG00000002835 and 540488
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Gene info
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Identity
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Gene
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Long gene nameSMAD1 antisense RNA 2
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GenBank acession
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Locus
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Discovery year2013-10-22
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Entrez gene record
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSMAD1 antisense RNA 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2013-10-22
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSMAD family member 1
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Synonyms gene
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Synonyms gene name
- MAD, mothers against decapentaplegic homolog 1 (Drosophila)
- SMAD, mothers against DPP homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SMAD family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglycyl-tRNA synthetase 1
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Synonyms gene
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Synonyms gene name
- Charcot-Marie-Tooth neuropathy 2D
- glycyl-tRNA synthetase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Aminoacyl tRNA synthetases, Class II
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data