Human DNA repair protein complementing XP-G cells (ERCC5)

Description

Recombinant Human DNA repair protein complementing XP-G cells(ERCC5),partial expressed in E.coli
Specifications

Uniprot ID: P28715; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 947-1186aa; Sequence information: Partial; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
Additional_information

MW: 30.8 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
Storage_and_shipping

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
Notes

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

DNA repair protein complementing XP-G cells ERCC5
Gene symbol

BIVM-ERCC5, IGHV3-71, ERCC5, HLA-G, POLH, NCAPG, FOLR3, SNRPG, PRKDC, GNAO1
Short name

DNA repair protein complementing XP-G cells (ERCC5)
Technique

dna
Species

Human, Humans
Alternative name

H. sapiens Desoxyribonucleic acid repair protein complementing XP-G cells (excision repair cross-complementing rodent repair deficiency, complementation family 5)
Alternative to gene target

excision repair cross-complementing rodent repair deficiency, complementation group 5, COFS3 and ERCC5-201 and ERCM2 and UVDR and XPG and XPGC, ERCC5 and IDBG-49163 and ENSG00000134899 and 2073, protein N-terminus binding, nuclei
Tissue

cells

Identity

HGNC:5621
Gene

IGHV3-71
Long gene name

immunoglobulin heavy variable 3-71 (pseudogene)
Synonyms gene
- IGHV3-G
Synonyms gene name
- immunoglobulin heavy variable 3-71
- immunoglobulin heavy variable 3-G pseudogene (provisional)
- immunoglobulin heavy variable 3-G (provisional)
- immunoglobulin heavy variable 3-71 pseudogene
Synonyms
- IGHV3-g
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28411
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151881

Identity

HGNC:3437
Gene

ERCC5
Long gene name

ERCC excision repair 5, endonuclease
Synonyms gene
- ERCM2
- XPGC
Synonyms gene name
- xeroderma pigmentosum, complementation group G
- excision repair cross-complementing rodent repair deficiency, complementation group 5
- excision repair cross-complementation group 5
Synonyms name
- Cockayne syndrome
GenBank acession
- X71342
Locus

13q33.1
Discovery year

2001-06-22
Entrez gene record

2073
Pubmed identfication
- 8088806
Classification
- Xeroderma pigmentosum complementation groups
- ERCC excision repair associated
VEGA ID

OTTHUMG00000017310
Locus Specific Databases
- LRG_464

Identity

HGNC:24304
Gene

NCAPG
Long gene name

non-SMC condensin I complex subunit G
Synonyms gene name
- non-SMC condensin I complex, subunit G
Synonyms
- FLJ12450
- hCAP-G
- CAP-G
- YCG1
Synonyms name
- chromosome condensation protein G
GenBank acession
- AF331796
Locus

4p15.31
Discovery year

2006-09-04
Entrez gene record

64151
Pubmed identfication
- 10910072
- 11136719
RefSeq identity
- NM_022346
Classification
- Armadillo like helical domain containing
- Condensin I subunits
VEGA ID

OTTHUMG00000128539

Identity

HGNC:4389
Gene

GNAO1
Long gene name

G protein subunit alpha o1
Synonyms gene name
- guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
Synonyms
- G-ALPHA-o
Locus

16q13
Discovery year

1988-04-24
Entrez gene record

2775
Pubmed identfication
- 1899283
- 11395521
RefSeq identity
- NM_020988
Classification
- G protein subunits alpha, group i
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000133241

Name

Targeted Gene Repair
Concept

Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
Qualifiers

legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data