anti-TCCR Antibody
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Catalog number2481
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTCCR Antibody: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
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Gene namesTCCR Antibody: CRL1, TCCR, WSX1, IL27R, IL-27RA, zcytor1, CRL1, UNQ296/PRO336, Interleukin-27 receptor subunit alpha, Cytokine receptor WSX-1, IL-27 receptor subunit alpha
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Antibodie s labelunlabelled serum
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PurityTCCR Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenTCCR antibody was made against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceTCCR antibody can be used for detection of TCCR by Western blot at 1 ug/mL. An approximately 70 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideTCCR Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTCCR antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr4759328
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Ncbi nrNP_004834
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KDa70 kDa
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Vial with antibodyin solution
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NCBI GENE nr9466
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GENE symbolIL27RA
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Antigene nameinterleukin 27 receptor, alpha
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SourceHomo sapiens
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Protein nrQ6UWB1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIL27RA
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Short nameanti-TCCR Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTCCR (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 27 receptor subunit alpha
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Synonyms gene name
- interleukin 27 receptor, alpha
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibronectin type III domain containing
- Interleukin receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data