Caspase-14 Antibody
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Catalog number3011-100
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PricePlease ask
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Size100 µg
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Antibody TargetCaspase-14
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Target Alternative NameCASP-14
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Antibody TypePolyclonal
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Species ReactivitiesHuman
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Immunogen SequenceSynthetic peptide corresponding sequence surrounding amino acid 176 of human Caspase-14
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AccessionP31944
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Gene Id23581
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
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PurificationAffinity purified
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ApplicationWestern blot
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Positive ControlJurkat cell lysate
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Application And UsagesWestern blot (1:100)
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DescriptionCaspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional descriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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French translationanticorps
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Gene target
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Gene symbolCASP14, CARD14
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Short nameCaspase-14 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namecaspase-14 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecaspase 14
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Synonyms gene name
- caspase 14, apoptosis-related cysteine protease
- caspase 14, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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Locus
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Discovery year1998-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 14
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Synonyms gene
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Synonyms gene name
- psoriasis susceptibility 2
- caspase recruitment domain family, member 14
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-09-19
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Entrez gene record
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Pubmed identfication
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Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- Caspase recruitment domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data