Anti-CHI3L1 (Polyclonal), ALEXA Fluor 594
-
Catalog numberGENTObs-10215R-A594
-
PricePlease ask
-
Size100 microliters
-
-
TypeConjugated Primary Antibody
-
Conjugated withALEXA FLUOR® 594
-
Host organismRabbit (Oryctolagus cuniculus)
-
Target Protein PeptideCHI3L1
-
SpecificityThis antibody reacts specifically with CHI3L1
-
ModificationNo modification has been applied to this antibody
-
Modification siteNone
-
ClonalityPolyclonal Antibody
-
ClonePolyclonal Antibodies
-
Concentration1ug per 1ul
-
Subcellular locationsCytoplasm, Secreted
-
Antigen SourceKLH conjugated synthetic peptide derived from Human CHI3L1
-
Gene ID1116
-
Swiss ProtP36222
-
ApplicationsFCM, IF(IHC-P)
-
Applications with corresponding dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
-
Cross reactive speciesHuman (Homo sapiens)
-
Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
-
Background informationCarbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
-
Purification methodPurified by Protein A.
-
StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
-
Excitation emission590nm/617nm
-
SynonymsGP39; ASRT7; GP-39; YKL4; CGP-39; YKL-4; YYL-4; HC-gp39; HCGP-3P; hCGP-39; Chitinase-3-like protein 1; 39 kDa synovial protein; Cartilage glycoprotein 39; CHI3L1
-
Also known asCHI3L1 Polyclonal Antibody
-
Other nameAnti-CHI3L1 Polyclonal
-
AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
PropertiesFor facs or microscopy Alexa 1 conjugate.
-
ConjugationAlexa Fluor, ALEXA FLUOR® 594
-
ConjugatedAlexa conjugate 1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
Gene target
-
Gene symbolCHI3L1
-
Short nameAnti-CHI3L1
-
TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 594
-
Alternative nameCHI3L1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namechitinase 3 like 1
-
Synonyms gene name
- chitinase 3-like 1 (cartilage glycoprotein-39)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1994-12-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Chitinases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data