Phospho-Caspase-6 (Ser257) antibody
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Catalog number
A1013-100
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Price
Please ask
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Size
100µl
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Antibody Target
Caspase-6 (Ser257)
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Target Alternative Name
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
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Antibody Type
Polyclonal
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Species Reactivities
Human, Mouse, Rat
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Immunogen Sequence
Synthesized peptide derived from human Caspase-6 around the phosphorylation site of S257
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Accession
P55212 (Human); O08738 (Mouse); O35397 (Rat)
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Gene Id
839 (Human); 12368 (Mouse)
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Appearance
Colorless liquid
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Form
Liquid
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Concentration
1 mg/ml
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Formulation
100ug (1 mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
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Purification
Affinity purified rabbit IgG
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Application
WB, IHC, IF, ELISA
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Positive Control
Western blot
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Application And Usages
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000
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Description
Caspases are the central components of the apoptotic response. Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Caspases are divided into two classes: the initiator caspases, which include caspase 2, 8, 9 and 10 and the effector caspases, which include caspases 3, 6 and 7. Effector caspases being activated by initiator caspases leads the proteolytic cleavage of a broad spectrum of cellular targets, which ultimately leads to cell death.
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans
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Handling
The antibody solution should be gently mixed before use
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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French translation
anticorps
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Gene target
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Short name
Phospho-Caspase-6 (Ser257) antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
phosphorilated-caspase-6 (Ser257) (antibody to-)
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
Product images
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