Anti-CRP (C11F2) Monoclonal, ALEXA Fluor 594
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Catalog number
GENTObsm-0391M-A594
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Price
Please ask
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Size
100 microliters
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Type
Conjugated Primary Antibody
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Conjugated with
ALEXA FLUOR 594
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Host organism
Mouse (Mus musculus)
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Target Protein Peptide
CRPC
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Specificity
Highly specific antibody against CRPC
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Modification
Not modified
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Clonality
Monoclonal Antibodies
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Clone
C11F2
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Concentration
1ug per 1ul
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Antigen Source
Recombinant CRP protein
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Gene ID
1401
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Applications
IF(IHC-P)
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Applications with corresponding dilutions
IF(IHC-P)(1:50-200)
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Cross Reactive species
Human (Homo sapiens)
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Cross Reactive Species details
No significant cross reactivity is observed
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Background information
C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
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Purification method
Purified by Protein G.
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Storage
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission
590nm/617nm
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Synonyms
C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
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Alternative name 1
CRP (C11F2) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative name 2
CRP (C11F2) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
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Advisory
Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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Properties
For facs or microscopy Alexa 1 conjugate.
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Conjugation
Alexa Fluor, ALEXA FLUOR® 594
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Conjugated
Alexa conjugate 1
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene
C reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Gene target
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Gene symbol
CRP, PPIAP10
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Short name
Anti-CRP (C11F2) Monoclonal,
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Technique
anti-, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 594
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Alternative name
Antibody toCRP (C11F2) monoclonal, ALEXA Fluor 594
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Alternative technique
antibodies
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Alternative to gene target
C-reactive protein, pentraxin-related, PTX1, CRP and IDBG-103911 and ENSG00000132693 and 1401, protein homodimerization activity, Extracellular, Crp and IDBG-205690 and ENSMUSG00000037942 and 12944, CRP and IDBG-630749 and ENSBTAG00000013907 and 527553
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Gene info
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Identity
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Gene
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Long gene name
C-reactive protein
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Synonyms gene name
- C-reactive protein, pentraxin-related
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Product files
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