Inhibitor of EGFR/HDAC/Her2 (CUDC-101; 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide, Mol wt 434.49, >99%)

• Catalog number
  SM-101020-50
• Price
  Please ask
• Size
  50 mg

• Stock availability
  Available
• Category
  Custom Service
• Antibody type
  N/A
• Antibody host
  N/A
• Antibody conjugate
  N/A
• Technical datasheet
  Contact Gentaur to request the datasheet or ask our specialists for more information.
• Notes
  The Inhibitor of EGFR/HDAC/Her2 (CUDC-101; 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide, Mol wt 434.49, >99%) is manufactured for Research Use Only or for diagnostics purposes.
• Other related products
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Inhibitor   EGFR/HDAC/Her2   CUDC-101   3-ethynylphenyl   amino   7-methoxyquinazolin-6-yl   oxy   N-hydroxyheptanamide   Mol   434  
• Gene symbol
  EGFR-AS1, EGILA, HDAC4, EGFR, HDAC9, RHBDF1, MIR101-2, MIR101-1, DERL2, MIR1302-6
• Short name
  Inhibitor of EGFR/HDAC/Her2 (CUDC-101; 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide, Mol wt 434 49, >99%)
• Species
  Human
• Alternative name
  suppressor on epidermal growth factor receptor/HDAC/Her2 (CUDC-101; 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide, Mol wt 434.49, >99%)
• Alternative to gene target
  epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217

Gene info

• Identity
  HGNC:40207
• Gene
  EGFR-AS1
• Long gene name
  EGFR antisense RNA 1
• Locus
  7p11.2
• Discovery year
  2012-11-06
• Entrez gene record
  100507500
• Pubmed identfication
  • 26271667
  • 28920960
• RefSeq identity
  • NR_047551
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156126

Gene info

• Identity
  HGNC:54482
• Gene
  EGILA
• Long gene name
  EGFR interacting lncRNA
• Synonyms
  • Lnc-EGFR
• Locus
  14q11.2
• Discovery year
  2019-09-27
• Pubmed identfication
  • 28541302
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:14063
• Gene
  HDAC4
• Long gene name
  histone deacetylase 4
• Synonyms gene
  • BDMR
• Synonyms gene name
  • brachydactyly-mental retardation syndrome
• Synonyms
  • KIAA0288
  • HDAC-A
  • HDACA
  • HD4
  • HA6116
  • HDAC-4
• GenBank acession
  • AB006626
• Locus
  2q37.3
• Discovery year
  2000-11-28
• Entrez gene record
  9759
• Pubmed identfication
  • 10206986
  • 10220385
  • 20691407
• RefSeq identity
  • NM_006037
• Classification
  • Histone deacetylases, class IIA
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133344

Gene info

• Identity
  HGNC:3236
• Gene
  EGFR
• Long gene name
  epidermal growth factor receptor
• Synonyms gene
  • ERBB
• Synonyms gene name
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
• Synonyms
  • ERBB1
  • ERRP
• Synonyms name
  • erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)
  • erb-b2 receptor tyrosine kinase 1
• Locus
  7p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  1956
• Pubmed identfication
  • 1505215
• RefSeq identity
  • NM_005228
• Classification
  • Erb-b2 receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000023661
• Locus Specific Databases
  • LRG_304

Gene info

• Identity
  HGNC:14065
• Gene
  HDAC9
• Long gene name
  histone deacetylase 9
• Synonyms
  • KIAA0744
  • HDAC
  • MITR
  • HD7
  • HDAC7B
• GenBank acession
  • AF124924
• Locus
  7p21.1
• Discovery year
  2002-09-06
• Entrez gene record
  9734
• Pubmed identfication
  • 10523670
  • 10487760
• Classification
  • Histone deacetylases, class IIA
• VEGA ID
  OTTHUMG00000152487

Gene info

• Identity
  HGNC:20561
• Gene
  RHBDF1
• Long gene name
  rhomboid 5 homolog 1
• Synonyms gene
  • C16orf8
• Synonyms gene name
  • chromosome 16 open reading frame 8
  • rhomboid family 1 (Drosophila)
  • rhomboid 5 homolog 1 (Drosophila)
• Synonyms
  • EGFR-RS
  • FLJ2235
  • Dist1
  • iRhom1
• GenBank acession
  • BC014425
• Locus
  16p13.3
• Discovery year
  2003-04-07
• Entrez gene record
  64285
• Pubmed identfication
  • 8318735
  • 15965977
• RefSeq identity
  • NM_022450
• Classification
  • Rhomboid family
• VEGA ID
  OTTHUMG00000060719

Gene info

• Identity
  HGNC:31489
• Gene
  MIR101-2
• Long gene name
  microRNA 101-2
• Synonyms gene
  • MIRN101-2
• Synonyms
  • hsa-mir-101-2
• Locus
  9p24.1
• Discovery year
  2004-04-23
• Entrez gene record
  406894
• RefSeq identity
  • NR_029836
• Classification
  • MicroRNA MIR101 family

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

Gene info

• Identity
  HGNC:17943
• Gene
  DERL2
• Long gene name
  derlin 2
• Synonyms gene name
  • Der1-like domain family, member 2
• Synonyms
  • F-LAN-1
  • FLANa
  • F-LANa
  • CGI-101
  • derlin-2
• GenBank acession
  • BC010890
• Locus
  17p13.2
• Discovery year
  2004-11-02
• Entrez gene record
  51009
• Pubmed identfication
  • 10810093
  • 11500051
• RefSeq identity
  • NM_016041
• Classification
  • Rhomboid family
• VEGA ID
  OTTHUMG00000102040

Gene info

• Identity
  HGNC:35298
• Gene
  MIR1302-6
• Long gene name
  microRNA 1302-6
• Synonyms gene
  • MIRN1302-6
• Synonyms
  • hsa-mir-1302-6
• Locus
  7p21.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302140
• RefSeq identity
  • NR_031635
• Classification
  • MicroRNA MIR1302 family

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