Fludarabine Phosphate

• Catalog number
  1763-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  [(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)- 3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid; Fludara
• Description
  A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-⍺, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
• CAS Number
  75607-67-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₁₃FN₅O₇P
• Molecular Weight
  365.21
• Cell Permeable
  No
• Purity
  ≥98%
• Solubilities
  DMSO or H₂O (5 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00866418
• PubChem CID
  30751
• PubChem CID Link
• SMILES
  C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)O)O)N=C(N=C2N)F
• InChi
  InChI=1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5-,6+,9-/m1/s1
• InChi Key
  GIUYCYHIANZCFB-FJFJXFQQSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fludarabine   Phosphate  
• Short name
  Fludarabine Phosphate
• Alternative name
  Fludarabine Phosphate

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