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Rabbit Anti Human PERK pThr892 Polyclonal

Rabbit Anti Human PERK pThr892 Polyclonal is available 14 times from Stressmark antibodies labs

SPC-963D-ALP | Rabbit Anti-Human PERK (pThr892) Polyclonal: Alkaline Phosphatase size: 100 µl | 443.94 USD

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SPC-963D-A390 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 390 size: 100 µl | 451.89 USD

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SPC-963D-A488 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 488 size: 100 µl | 450.75 USD

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SPC-963D-A565 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 565 size: 100 µl | 450.75 USD

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SPC-963D-A594 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 594 size: 100 µl | 450.75 USD

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SPC-963D-A633 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 633 size: 100 µl | 450.75 USD

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SPC-963D-A655 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 655 size: 100 µl | 450.75 USD

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SPC-963D-A680 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 680 size: 100 µl | 450.75 USD

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SPC-963D-A700 | Rabbit Anti-Human PERK (pThr892) Polyclonal: ATTO 700 size: 100 µl | 450.75 USD

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SPC-963D-BI | Rabbit Anti-Human PERK (pThr892) Polyclonal: Biotin size: 100 µl | 446.21 USD

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SPC-963D-HRP | Rabbit Anti-Human PERK (pThr892) Polyclonal: HRP size: 100 µl | 437.13 USD

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SPC-963D-P594 | Rabbit Anti-Human PERK (pThr892) Polyclonal: PE/ATTO 594 size: 100 µl | 458.70 USD

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SPC-963D-RPE | Rabbit Anti-Human PERK (pThr892) Polyclonal: RPE size: 100 µl | 447.35 USD

Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test StressMark antibodies supplies antibodies that are for research of human proteins.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name Oryctolagus cuniculus
Gene targetPERK pThr892 RPE
Short name Rabbit Anti- PERK (pThr892) Polyclonal: RPE
Technique anti-Human, Polyclonal, Rabbit, anti
Label rpe
Alternative name production species: rabbit antibody to-H. sapiens PERK (pThr892) polyclonal: RPE
1. Gene info
Identity 3255
Gene EIF2AK3
Long gene name eukaryotic translation initiation factor 2 alpha kinase 3
Synonyms
  • PEK
  • PERK
GenBank acession
  • AF110146
Locus 2p11.2
Discovery year 1999-06-14
Entrez gene record 9451
Pubmed identfication
  • 10026192
  • 10575235
RefSeq identity
  • NM_004836
Havana BLAST/BLAT OTTHUMG00000155046
Locus Specific Databases
  • LRG_1024
2. Gene info
Identity 10293
Gene RPE
Long gene name ribulose-5-phosphate-3-epimerase
Locus 2q34
Discovery year 2001-06-22
Entrez gene record 6120
RefSeq identity
  • NM_006916
Havana BLAST/BLAT OTTHUMG00000154690
MeSH Data
Name Blotting, Western
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Product images
    #Human#.jpg

SPC-963D-STR | Rabbit Anti-Human PERK (pThr892) Polyclonal: Streptavidin size: 100 µl | 448.48 USD

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PubMed number Refer to PubMed
Net weight (g) 0.1
Recommended buffer for storage PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Antibody's reactivity Human
Warning information Non-hazardous
Raised in Rabbit
NCBI number NP_004827
Gene number 9451
Released date 29/Aug/2016
Immunogen A phospho-specific peptide corresponding to residues surrounding Thr892 of human PERK (AA889-895)
Antibody's other name Eif2ak3 Antibody, Eukaryotic translation initiation factor 2 alpha kinase 3 Antibody, Heme regulated EIF2 alpha kinase Antibody, HRI Antibody, HsPEK Antibody, Pancreatic eIF2-alpha kinase Antibody, PEK Antibody, PRKR-like Endoplasmic Reticulum kinase Antibody, WRS Antibody
Protein number Q9NZJ5
Antibody's recommended dilutions for use WB (1:250); optimal dilutions for assays should be determined by the user.
Tested applications To be tested
Antibody's datasheet Contact our support service to receive datasheet or other technical documentation.
Total weight (kg) 1.4
Stock availabilit In Stock
Scientific context PERK (eukaryotic translation initiation factor 2-α kinase 3, eIF2α kinase 3, PEK, WRS) is a Ser/Thr protein kinase, type I membrane protein of the endoplasmic reticulum that is abundant in secretory tissues and is inducible by ER-stress. PERK phosphorylates the α subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, a reduction of translation initiation and repression of global protein synthesis. PERK may serve as an effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1. PERK dimerizes with HSPA5/BIP in resting cells and oligomerizes in ER-stressed cells. Perturbation in protein folding in the endoplasmic reticulum (ER) can promote dissociation from HSPA5/BIP and oligomerization, resulting in autophosphorylation and kinase activity induction.
Antibody's target Human PERK (pThr892)
Certificate of analysis A 1:250 dilution of SPC-963 was sufficient for detection of PERK (pThr892) in 10 µg of HepG2 cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Tissue specificity See included datasheet or contact our support service.
Antibody's full description Rabbit Anti-Human PERK (pThr892) Polyclonal
Country of production Canada
Antibody's purified from Peptide Affinity Purified
Antibody's concentration See included datasheet or contact our support service
Tested reactivity To be tested
Antibody in cell Endoplasmic Reticulum Membrane
Antibody's category Polyclonal Antibodies
Representative figure link No Data Available
Bibliography Refer to PubMed
Verified applications WB, AM
Antibody's specificity Detects 125.147 kDa.
Storage recommendations -20°C
Shipping recommendations Blue Ice or 4°C
Host Rabbit
Species Human
Alternative technique polyclonals
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Rabbit Anti-Human PERK (pThr892) Polyclonal: RPE
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+32-(0)1-658-90-45 lieven@gentaur.com
  • PERK
  • pThr892
  • Alkaline
  • Phosphatase
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