MAP3K4/MEK kinase-4 Antibody
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Catalog number
bs-11883R
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Price
Please ask
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Size
0.1ml
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Long name
MAP3K4/MEK kinase-4 Primary Polyclonal Antibody
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Also known as
MAP3K4/MEK kinase-4 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
MAP3K4/MEK kinase-4
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Specificity
This is a highly specific antibody against MAP3K4/MEK kinase-4.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4
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Tested Applications
IHC-P, IF(IHC-P)
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Recommended dilutions
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
FLJ42439; KIAA0213; M3K4_HUMAN; MAP three kinase 1; MAP3K4; MAPK/ERK kinase kinase 4; MAPKKK4 antibodyMEK kinase 4; MEKK 4; MEKK4; Mitogen-activated protein kinase kinase kinase 4; MTK1; PRO0412; RP3-473J16.4
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
MAP3K4-AS1, MAP3K4
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Short name
Anti-MAP3K4/MEK kinase-4
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
MAP3K4/MEK kinase-4 Polyclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
mitogen-activated protein kinase kinase kinase 4, MAPKKK4 and MEKK 4 and MEKK4 and MTK1 and PRO0412, MAP3K4 and IDBG-98770 and ENSG00000085511 and 4216, transferase activity, Cytoplasm, Map3k4 and IDBG-136472 and ENSMUSG00000014426 and 26407, MAP3K4 and IDBG-635619 and ENSBTAG00000020079 and 511779
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Gene info
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Identity
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Gene
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Long gene name
MAP3K4 antisense RNA 1
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GenBank acession
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Locus
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Discovery year
2020-06-03
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Pubmed identfication
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Classification
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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