HDAC3 (Ser424) Antibody
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Catalog numberbs-3174R
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PricePlease ask
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Size0.1ml
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Long nameHDAC3 (Ser424) Primary Polyclonal Antibody
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Also known asHDAC3 (Ser424) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenHDAC3 Ser424
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SpecificityThis is a highly specific antibody against HDAC3 Ser424.
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Modification sPhosphorylation
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Modification site sSer424
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424
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Gene ID number8841
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesHDAC3 phospho S424; HDAC3 phospho Ser424; p-HDAC3 Ser424; RPD3 2; RPD3-2; HD 3; HD3; HDAC 3; Histone deacetylase 3 HD3 RPD3-2; histone deacetylase 3; RPD 3; RPD3; SMAP 45; SMAP-45; SMAP45; HDAC3_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHDAC3
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Short nameAnti-HDAC3 Ser424
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameHDAC3 (Ser424) Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targethistone deacetylase 3, HD3 and RPD3 and RPD3-2, HDAC3 and IDBG-50725 and ENSG00000171720 and 8841, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac3 and IDBG-140814 and ENSMUSG00000024454 and 15183, HDAC3 and IDBG-646121 and ENSBTAG00000017360 and 404125
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Gene info
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Identity
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Gene
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Long gene namehistone deacetylase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NCoR/SMRT transcriptional repression complex subunits
- Histone deacetylases, class I
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data