Hinokitiol, Iron Chelator antioxidant

  • Catalog number
    SIH-151-50MG
  • Price
    Please ask
  • Size
    50 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    499-44-5
  • Description
    Iron Chelator antioxidant
  • Molecular weight
    164,2 g/mol
  • Primary research fields
    Cancer, Oxidative Stress
  • Other name
    2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one
  • Product category
    Small Molecules
  • Product type
    Antioxidant
  • Chemical formula
    C10H12O2
  • Origin
    Synthetic
  • Purity pourcentage
    >98%
  • Soluble in
    Soluble in DMSO or ethanol (25 mg/ml)
  • Physical appearance
    White Solid
  • Storage recommendations
    -20ÂșC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
  • PubChem number
    3611
  • Scientific context
    Hinokitiol is a natural monoterpenoid. It is a potent metal chelator that induces differentiation and apoptosis in teratocarcinoma F9 cells (1), mediated by activation of caspase-3 (2). It also inhibits tyrosinase most likely via metal chelation (3).
  • Bibliography
    1. Tanaka T., et al. (1999) Cell Biol Int. 23(8): 541-550. 2. Ido Y., et al. (1999) Cell Prolif. 32(1): 63-73 3. Kim D.S., et al. (2004) Arch Pharm Res. 27(3): 334-339.
  • Release date
    16-May-2011
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of Hinokitiol (SIH-151), a Iron Chelator antioxidant. CAS #: 499-44-6. Molecular Formula: C10H12O3. Molecular Weight: 165.2 g/mol. Chemical structure of Hinokitiol, a Iron Chelator antioxidant (SIH-151). CAS # 499-44-6. Molecular Formula: C10H12O3.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.05
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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