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LIMKi 3 for cell activation

LIMKi 3 for cell activation is available 2 times from Biovision labs

B1095-25 | LIMKi 3 for cell activation size: 25 mg | 667.14 USD

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B1095-5 | LIMKi 3 for cell activation size: 5 mg | 211.04 USD

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Other name N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide ; BMS 5
Supplied with N/A
Description LIMKi 3 is a potent, and cell-permeable inhibitor of LIMK1 (IC₅₀ = 7 nM) and LIMK2 (IC₅₀ = 8 nM) and inhibits coflin phosphorylation in MDA-MB-231 breast cancer cells without affecting tubulin polymerization or inducing cytotoxicity. It also reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
Category Biochemicals
Molecular formula C₁₇H₁₄Cl₂F₂N₄OS
Is it cell-permeable? Yes
Molecular weight 431.29
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 1338247-35-0
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance White Solid
Reconstitute instructions DMSO (>40mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetLIMKi for activation
Short name LIMKi 3 for activation
Technique activation
Alternative name LIMKi 3 to measure cellular activation
Tissue cell
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