Tankyrase Antibody, ALEXA FLUOR 555
-
Catalog number
bs-9104R-A555
-
Price
Please ask
-
Size
100ul
-
-
Long name
Tankyrase Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
-
Also known as
Anti-Tankyrase PAb ALEXA FLUOR 555
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 555
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
Tankyrase
-
Specificity
This is a highly specific antibody against Tankyrase.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen range
1140-1171/1327
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tankyrase
-
Gene ID Number
8658
-
Swiss Prot
O95271
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
553nm/568nm
-
Synonyms
TIN1; ARTD5; PARPL; TINF1; TNKS1; pART5; PARP5A; PARP-5a; Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I; TNKS
-
Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR 555
-
French translation
anticorps
-
Gene target
-
Gene symbol
TNKS1BP1, TNKS, TNKS2
-
Short name
Anti-Tankyrase
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 555
-
Alternative name
Tankyrase Polyclonal Antibody, ALEXA FLUOR 555
-
Alternative technique
antibodies
-
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
tankyrase
-
Synonyms gene name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1999-01-08
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Poly(ADP-ribose) polymerases
- Sterile alpha motif domain containing
- Ankyrin repeat domain containing
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
tankyrase 2
-
Synonyms gene name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2001-05-10
-
Entrez gene record
-
RefSeq identity
-
Classification
- Poly(ADP-ribose) polymerases
- Sterile alpha motif domain containing
- Ankyrin repeat domain containing
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products