TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant
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Catalog number
7254-1000
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Price
Please ask
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Size
1 mg
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Synonyms
ECAT8
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Alternative_names
ECAT8
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Description
Involved in RISC complex and interaction with AEG-1 oncogene
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥98%
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Assay
SDS-PAGE
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Molecular Weight
13 kDa
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Storage Temp
-80°C
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Shipping
Dry Ice
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Shelf Life
12 months
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Concentration
2 mg/ml
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Appearance
Liquid
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Physical form description
rh-TDRD12-BD2 is supplied as a solution in PBS Buffer containing 10% glycerol
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Background Information
Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TDRD12
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Short name
TDRD12-BD2 (908-999 aa) (His-Tagged), recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Label
his-tagged
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Species
Human, Humans
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Alternative name
TDRD12-BD2 (908-999 aa) (histidine-Tagged), H. sapiens Rec.
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Alternative technique
rec
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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