Prostate Specific Antigen (PSA)

• Catalog number
  GEN438182
• Price
  Please ask
• Size
  100ug

• Also known as
  Prostate Specific Antigen
• Other names
  prostate-specific antigen isoform 3 preproprotein; Prostate-specific antigen; prostate-specific antigen; seminin; P-30 antigen; kallikrein-3; semenogelase; gamma-seminoprotein; prostate specific antigen; kallikrein-related peptidase 3; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  KLK3
• Gene name synonims
  N/A
• Other gene names
  KLK3; KLK3; APS; PSA; hK3; KLK2A1; APS; PSA; Seminin
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  SPM352
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
• Description
  Antigens are peptides or recombinant or native dependent on the production method.

• Gene target
  Prostate   Specific   PSA  
• Gene symbol
  KLK3, NPEPPS, PSAT1
• Short name
  Prostate Specific Antigen (PSA)
• Technique
  antigen, antigenes
• Alternative name
  Anti-Prostate Specific Antigen (PSA)
• Alternative technique
  antigenes
• Tissue
  prostate

Gene info

• Identity
  HGNC:6364
• Gene
  KLK3
• Long gene name
  kallikrein related peptidase 3
• Synonyms gene
  • APS
• Synonyms gene name
  • kallikrein 3, (prostate specific antigen)
• Synonyms
  • PSA
• GenBank acession
  • X14810
• Locus
  19q13.33
• Discovery year
  2001-06-22
• Entrez gene record
  354
• Pubmed identfication
  • 2456523
  • 2436946
  • 16800724
  • 16800723
• RefSeq identity
  • NM_145864
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000182867

Gene info

• Identity
  HGNC:7900
• Gene
  NPEPPS
• Long gene name
  aminopeptidase puromycin sensitive
• Synonyms
  • PSA
  • MP100
• Synonyms name
  • puromycin-sensitive aminopeptidase
  • metalloproteinase MP100
• GenBank acession
  • Y07701
• Locus
  17q21.32
• Discovery year
  1999-12-09
• Entrez gene record
  9520
• Pubmed identfication
  • 9048733
  • 10329370
• RefSeq identity
  • NM_006310
• Classification
  • M1 metallopeptidases
  • Aminopeptidases
• VEGA ID
  OTTHUMG00000165471

Gene info

• Identity
  HGNC:19129
• Gene
  PSAT1
• Long gene name
  phosphoserine aminotransferase 1
• Synonyms
  • PSA
  • PSAT
• Synonyms name
  • phosphoserine transaminase
• GenBank acession
  • BC004863
• Locus
  9q21.2
• Discovery year
  2003-05-19
• Entrez gene record
  29968
• Pubmed identfication
  • 12633500
  • 3651428
• RefSeq identity
  • NM_021154
• VEGA ID
  OTTHUMG00000020066

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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