anti-DRAM Antibody

• Catalog number
  4035
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  DRAM Antibody: Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles. It has been suggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA, Bax, etc., and that the signaling pathways regulated by these genes together promote a full cell death response. By itself, DRAM cannot induce apoptosis, but the fact that it is inactivated in certain cancers highlights the importance of DRAM and suggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist.
• Gene names
  DRAM Antibody: DRAM, DRAM, DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator
• Antibodie s label
  unlabelled serum
• Purity
  DRAM Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  DRAM antibody was made against a 16 amino acid synthetic peptide from near the amino terminus of human DRAM.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  DRAM antibody can be used for detection of DRAM by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  DRAM Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  DRAM antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  22450862
• Ncbi nr
  AAH18435
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  55332
• GENE symbol
  DRAM
• Antigene name
  damage-regulated autophagy modulator
• Source
  Homo sapiens
• Protein nr
  Q8N682
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DRAM  
• Gene symbol
  DRAM1
• Short name
  anti-DRAM Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toDRAM (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25645
• Gene
  DRAM1
• Long gene name
  DNA damage regulated autophagy modulator 1
• Synonyms gene name
  • DNA-damage regulated autophagy modulator 1
• Synonyms
  • FLJ11259
  • DRAM
• Synonyms name
  • damage-regulated autophagy modulator
• GenBank acession
  • BC018435
  • DA721965
• Locus
  12q23.2
• Discovery year
  2009-06-12
• Entrez gene record
  55332
• Pubmed identfication
  • 16839881
• RefSeq identity
  • NM_018370
• VEGA ID
  OTTHUMG00000170447

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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