anti-TOX Antibody
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Catalog number6987
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTOX Antibody: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
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Gene namesTOX Antibody: TOX1, KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX
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Antibodie s labelunlabelled serum
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PurityTOX Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toNo alternatively spliced transcript variants have been observed.
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AntigenTOX antibody was made against a 17 amino acid synthetic peptide near the amino terminus of human TOX.
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Immuno applicationELISA, Western Blot, immuno fluorescence
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Antibody adviceTOX antibody can be used for detection of TOX by Western blot at 1 - 2 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideTOX Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTOX antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr7662322
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Ncbi nrNP_055544
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KDa58 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr9760
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GENE symbolTOX
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Antigene namethymocyte selection-associated high mobility group box protein TOX
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Sourcehomo sapiens
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Protein nrO94900
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDUOX2, TOX
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Short nameanti-TOX Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTOX (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetthymocyte selection-associated high mobility group box, TOX1, TOX and IDBG-22820 and ENSG00000198846 and 9760, DNA binding, nuclei, Tox and IDBG-128779 and ENSMUSG00000041272 and 252838, TOX and IDBG-644500 and ENSBTAG00000004954 and 525888
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Gene info
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Identity
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Gene
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Long gene namedual oxidase 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namethymocyte selection associated high mobility group box
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Synonyms
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Locus
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Discovery year2007-03-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
