sRANK Ligand, murine recombinant

• Catalog number
  4557-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
• Alternative_names
  Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
• Description
  An osteoclast differentiation and activation factor
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Purity
  ≥98%
• Biological activity
  Measured by its ability to induce osteoclast formation in RAW264.7 cells using a concentration of 5-10 ng/ml.
• Results
  5-10 ng/ml
• Molecular Weight
  19.4 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from 5 mM Tris, pH 7.6 + 75 mM NaCl
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 mg /ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
• Background Information
  Murine RANK (receptor activator of NF-kB) is a newly discovered member of the TNFR family, identified as a dendritic cell membrane protein. The recombinant murine sRANK Ligand is a soluble 19.4 kDa protein, comprising the 174 amino acid residue TNF homologous region of RANKL.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional description
  FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  sRANK   Ligand   murine  
• Short name
  sRANK Ligand, murine recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  sRANK Ligand, murine Rec.
• Alternative technique
  rec

MeSH Data

• Name
  Urine Specimen Collection
• Concept
  Scope note: Methods or procedures used to obtain samples of URINE.
• Tree numbers
  • E01.370.225.998.762
  • E05.200.998.762
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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