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anti MMP 9 Antibody

anti MMP 9 Antibody is available 3 times from Biovision labs

5565-100 | anti-MMP-9 Antibody size: MMP-9 Antibody | 383.49 USD

Catalog number 5565-100
Supplier Biovision
Price383.49 USD
Size MMP-9 Antibody
Alternative names of antibody target: MMP9, MMP-9, MMP 9, Matrix metalloproteinase-9, Matrix metalloproteinase 9, Gelatinase B, 92kDa type IV collagenase
Background information: The mammalian Matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a single peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP. MMP-9 (92 kDa type IV collagenase, Gelatinase-B) contains the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.
This antibody reacts with: rat
Immunogene sequence: E. coli-expressed active rat 92-kDa type IV collagenase
Concentration of antibody: 0.5 mg/ml
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified rabbit anti-rat MMP-9 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
This antibody has been succesfully tested for use in following methods: Western blot, Immunoprecipitation, Immunohistochemistry
Recommended usage: Western blot analysis (0.5-4 µg/ml), immunoprecipitation (4-8 µg/ml), and Immunohistochemistry (20-40 µg/ml). However, the optimal conditions should be determined individually.
1. Gene info
Identity34269
GeneRNU6-9
Long gene name RNA, U6 small nuclear 9
Synonyms
Locus19p13.3
Discovery year 2008-06-10
Entrez gene record101954271
Pubmed identfication
RefSeq identity
Classification
  • Small nuclear RNAs
2. Gene info
Identity7176
GeneMMP9
Long gene name matrix metallopeptidase 9
Synonyms gene
Synonyms gene name
  • matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Discovery year 1990-03-14
Entrez gene record4318
Pubmed identfication
Classification
  • M10 matrix metallopeptidases
Havana BLAST/BLATOTTHUMG00000033044
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedUp-regulation of vascular endothelial growth factor by membrane-type 1 matrix metalloproteinase stimulates human glioma xenograft growth and angiogenesis.
data provide evidence for an additional mechanism for post-translational control of membrane type 1 matrix metalloproteinase (MT1-MMP) activity and suggest that glycosylation of MT1-MMP may regulate its substrate targeting
E1AF positively regulates transcription from MT1-MMP genes, which plays an important role in invasion and metastasis of squamous cell carcinoma of the tongue by converting pro-MMP-2 into active-MMP-2
Pericellular collagenolysis is regulated by correct molecular assembly of the membrane-anchored collagenase, thereby governing the directionality of the cell to migrate in tissue.
Lutheran blood group glycoprotein (Lu) is one of the proteins cleaved by MT1-MMP.
these results suggest that cleavage of lipid-free apoA-I by MMP-14 may contribute to reduced HDL formation.
Thus, our findings reveal that MMP14 is necessary to efficiently reduce the physical restraints imposed by collagen-I during branching morphogenesis.
This study demonistrated that Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases
possible involvement of membrane-type 1 matrix metalloproteinase processing of erythropoietin-producing hepatocellular receptor-2in invasiveness of cutaneous cutaneous squamous cell carcinoma
We conclude that ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas, which qualifies these proteins in diagnosis and therapy.
InterProMetallopeptidase, catalytic domain  (A2MP1)  (AADAC)  (ABCA12)  (ABCA3)  (ABHD14B)  (ABI1)  (ABI3)  (ABL1)  (ABLIM3)  (ABRA)  (ACPP)  (ADAMTS3)  (ADAMTS6)  (ADCY10P1)  (ADIPOQ)  (ADPGK)  (ADRA1B)  (ADSL)  (AFDN)  (AGAP11)  (AKIRIN1P1)  (AKR1A1)  (AKR1C6P)  (ALKBH8)  (AMMECR1)  (AMMECR1-IT1)  (ANAPC10)  (ANKLE1)  (ANKRD19P)  (ANKRD27)  (ANO10)  (ANO2)  (ANO4)  (ANO7L1)  (ANO8)  (ANO9)  (AP1M2)  (AP1S3)  (AP2M1)  (AP4B1)  (AP4E1)  (APOL1)  (ARCN1)  (ARHGAP26)  (ARHGAP27)  (ARHGAP33)  (ARHGEF11)  (ARL6IP6)  (ARMC6)  (ARMH3)  (ARPC1B)  (ARPC3P1)  (ARPC5)  (ARPC5L)  (ARR3)  (ASAP1-IT1)  (ASAP1-IT2)  (ASAP2)  (ASPH)  (ASTN1)  (ATAD3A)  (ATF7)  (ATF7IP)  (ATG4C)  (ATP5MC3)  (ATP5ME)  (ATP5S)  (ATPAF1)  (ATXN7L3B)  (AVIL)  (B3GAT2)  (B4GALT2)  (B9D1)  (BABAM2)  (BACH2)  (BCL2L1)  (BCL6)  (BCL7A)  (BEND3)  (BEST4)  (BFAR)  (BGLT3)  (BNIP2)  (BPI)  (BRCA1P1)  (BRD7)  (BRE-AS1)  (BRI3)  (BRI3BPP1)  (BRINP1)  (BRIP1)  (BSDC1)  (BTBD18)  (BTBD9)  (BUD13)  (C2)  (CA8)  (CABS1)  (CACHD1) 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Peptidoglycan binding-like
Hemopexin-like domain
Peptidase M10A, matrix metallopeptidase, C-terminal
Matrix metalloproteinase-14  (MMP14)
Hemopexin, conserved site
Peptidase M10A
Peptidase, metallopeptidase  (LMLN)
Peptidase M10A, stromelysin-type
Hemopexin-like repeats
Product images
    #0#.jpegMMP-9 Antibody

3969-200 | anti-MMP-9 Antibody size: MMP-9 Antibody | 358.53 USD

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3529-100 | anti-MMP-9 Antibody size: MMP-9 Antibody | 358.53 USD

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Target of this antibody: MMP-9
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Purification method: Affinity purified
Shipping conditions: gel pack
Antibody host: Rabbit
How to handle this antibody: The antibody solution should be gently mixed before use.
Clonality of antibody: Polyclonal
Form of antibody: Liquid
Isotype: Rabbit IgG
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetMMP-9
Short name anti-MMP-9 Antibody
Technique Antibody, anti
Alternative name antibody to-MMP-9 (Antibody to)
Alternative technique antibodies
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