Emetine dihydrochloride hydrate

• Catalog number
  B2339-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine, dihydrochloride, hydrate,Emetine hydrochloride hydrate
• Description
  An alkaloid derived from ipecac root. Irreversibly blocks protein synthesis by inhibiting the movement of ribosome along the mRNA. Induces hypotension by blocking adrenoreceptors. Inhibits DNA replication in the early S phase. Inhibits HIF-1 activation by hypoxia. Induces apoptosis in leukemia cells. Also, selectively inhibits multiple glioblastoma (GBM) stem cells-enriched cultures.
• CAS Number
  7083-71-8
• Structure Available
  Yes
• Molecular Formula
  C₂₉H₄₀N₂O₄.2HCl. xH₂O
• Molecular Weight
  553.56 (anhydrous basis)
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  >100 mg/ml (H₂O) in 0
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A protein synthesis inhibitor
• Storage Condition
  4ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00149309
• PubChem CID
  201899
• PubChem CID Link
• SMILES
  CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC.O.Cl.Cl
• InChi
  InChI=1S/C29H40N2O4.2ClH.H2O/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24;;;/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3;2*1H;1H2/t18-,21-,24+,25-;;;/m0.../s1
• InChi Key
  IZTPMTAWOCEKKM-VXMYZLRESA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Emetine   dihydrochloride   hydrate  
• Short name
  Emetine dihydrochloride hydrate
• Alternative name
  Emetine dihydrochloride hydrate

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