Anti-D2HGDH Antibody

• Catalog number
  A1382-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  D2HGDH
• Target Alternative Name
  D-2-hydroxyglutarate dehydrogenase, D2HGDH, D2HGD, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein
• Antibody Type
  Polyclonal
• Species Reactivities
  Acidaminococcus fermentans
• Immunogen Sequence
  Full-length D2HGDH from Acidaminococcus fermentans
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Western blot
• Application And Usages
  Western blot: 1-4 µg/ml
• Description
  D-2-hydroxyglutarate (D2HG) level is significantly increased in metabolic diseases and various cancers such as acute myeloid leukemia. Studies suggest that the detection of D2HG serves as a biomarker assay related to IDH (isocitrate dehydrogenase) mutations. D2HGDH is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D2HG to α-ketoglutarate. D2HGDH is a key enzyme to distinguish between two metabolites, D2HG and L-2-hydroxyglutarate (L2HG), during biomarker assays.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  D2HGDH  
• Gene symbol
  D2HGDH
• Short name
  Anti-D2HGDH Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toD2HGDH (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28358
• Gene
  D2HGDH
• Long gene name
  D-2-hydroxyglutarate dehydrogenase
• Synonyms
  • MGC25181
  • D2HGD
  • FLJ42195
• GenBank acession
  • AK091725
• Locus
  2q37.3
• Discovery year
  2006-03-09
• Entrez gene record
  728294
• Pubmed identfication
  • 15070399
  • 15609246
• RefSeq identity
  • NM_152783
• VEGA ID
  OTTHUMG00000151474
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products