K-7174 dihydrochloride
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Catalog number9478-5
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PricePlease ask
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Size5 mg
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Alternative_name1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl)-1,4-diazepane dihydrochloride
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DescriptionK-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α. K7174 also ameliorated anemia induced by inflammatory cytokines in mice.
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CAS Number191089-60-8
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Structure AvailableYes
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Molecular FormulaC₃₃H₅₀BrCl₂N₂O6
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Molecular Weight641.67
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>6 mg/ml)
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HandlingProtect from air and light
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Tag LineA novel cell adhesion inhibitor
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Storage Condition-20°C
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Shipping ConditionGel pack
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Shelf Life36 months
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SMILESCOC1=C(OC)C(OC)=CC(/C=C/CCCN2CCN(CCC/C=C/C3=CC(OC)=C(OC)C(OC)=C3)CCC2)=C1.[H]Cl.[H]Cl
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InChiInChI=1S/C33H48N2O6.2ClH/c1-36-28-22-26(23-29(37-2)32(28)40-5)14-9-7-11-16-34-18-13-19-35(21-20-34)17-12-8-10-15-27-24-30(38-3)33(41-6)31(25-27)39-4;;/h9-10,14-15,22-25H,7-8,11-13,16-21H2,1-6H3;2*1H/b14-9+,15-10+;;
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InChi KeyJKAQFPBRMVEHBD-CHBZAFCASA-N
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MSDS AvailableYes
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Gene target
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Gene symbolH4C13, TUBA1B, RAP2A, GPC4, CPAMD8, H2BC10, RAP1B, KRAS
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Short nameK-7174 dihydrochloride
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Alternative nameK-7174 dihydrochloride
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Gene info
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Identity
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Gene
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Long gene nameH4 clustered histone 13
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Synonyms gene
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Synonyms gene name
- H4 histone family, member K
- histone 1, H4l
- histone cluster 1, H4l
- histone cluster 1 H4 family member l
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H4 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametubulin alpha 1b
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAP2A, member of RAS oncogene family
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglypican 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Glypicans
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameC3 and PZP like alpha-2-macroglobulin domain containing 8
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C3 and PZP like, alpha-2-macroglobulin domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH2B clustered histone 10
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Synonyms gene
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Synonyms gene name
- H2B histone family, member K
- histone 1, H2bi
- histone cluster 1, H2bi
- histone cluster 1 H2B family member i
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H2B histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAP1B, member of RAS oncogene family
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Synonyms
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameKRAS proto-oncogene, GTPase
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Synonyms gene
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Synonyms gene name
- v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
- v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- Kirsten rat sarcoma viral oncogene homolog
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-06-02
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Entrez gene record
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
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Locus Specific Databases
