Recombinant Human Cbl-c / CBL-3 Protein (His & GST tag) 100µg
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Catalog number
PKSH030531-100µg
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Price
Please ask
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Size
100µg
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Synonym
CBL-3;CBL-SL;RNF57
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Activity
NA
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Sequence
Met1-Ala474
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Fusion tag
N-His & GST
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Accession
AAH28915.1
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Expressed Host
Baculovirus-Insect Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞95 % as determined by SDS-PAGE
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Endotoxin
＜1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
80.2 kDa
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AP Mol Mass
66 kDa
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Formulation
Lyophilized from sterile 20mM Tris, 500mM Nacl, 10% glycerol, pH 8.0
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Reconstitution
Please refer to it for detailed information.
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Background
CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CBLC, CBL, MGST3, CBLB, MIR1302-3, MIR509-3, MIR7-3, PIRC14, PIRC12
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Short name
Recombinant Cbl-c / CBL-3 Protein (His & GST tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase-c / Cbl proto-oncogene, E3 ubiquitin protein ligase-3 Protein (histidine & GST detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
Cbl proto-oncogene, E3 ubiquitin protein ligase, C-CBL and CBL2 and FRA11B and NSLL and RNF55, CBL and IDBG-74417 and ENSG00000110395 and 867, ephrin receptor binding, nuclei, Cbl and IDBG-155970 and ENSMUSG00000034342 and 12402, CBL and IDBG-631730 and ENSBTAG00000006817 and 527418
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Gene info
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Identity
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Gene
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Long gene name
Cbl proto-oncogene C
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Synonyms gene name
- Cas-Br-M (murine) ectropic retroviral transforming sequence c
- Cas-Br-M (murine) ecotropic retroviral transforming sequence c
- Cbl proto-oncogene C, E3 ubiquitin protein ligase
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
Cbl proto-oncogene
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Synonyms gene
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Synonyms gene name
- Cas-Br-M (murine) ecotropic retroviral transforming sequence
- Cbl proto-oncogene, E3 ubiquitin protein ligase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
Gene info
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Identity
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Gene
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Long gene name
Cbl proto-oncogene B
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Synonyms gene name
- Cas-Br-M (murine) ectropic retroviral transforming sequence b
- Cas-Br-M (murine) ecotropic retroviral transforming sequence b
- Cbl proto-oncogene B, E3 ubiquitin protein ligase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1995-12-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
microRNA 1302-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 509-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 7-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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