anti-MCM2 Antibody
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Catalog number28-535
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PricePlease ask
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Size100 ug
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Gene infoThe protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
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Gene namesMCM2, BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by protein A chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM2.
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Immuno applicationELISA, Western Blot
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Antibody adviceMCM2 antibody can be used for detection of MCM2 by ELISA at 1:312500. MCM2 antibody can be used for detection of MCM2 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store MCM2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman
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Omim nr33356547
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Ncbi nrNP_004517
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KDa99 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr4171
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GENE symbolMCM2
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Antigene nameminichromosome maintenance complex component 2
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SourceHomo sapiens
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Protein nrP49736
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMCM7, MCM2
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Short nameanti-MCM2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toMCM2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameminichromosome maintenance complex component 7
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Synonyms gene
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Synonyms gene name
- minichromosome maintenance deficient (S. cerevisiae) 7
- MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-12-13
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Entrez gene record
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Pubmed identfication
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Classification
- MCM family
- MicroRNA protein coding host genes
- minichromosome maintenance 2-7 complex
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameminichromosome maintenance complex component 2
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Synonyms gene
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Synonyms gene name
- minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin)
- MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-09-30
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Entrez gene record
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Pubmed identfication
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Classification
- MCM family
- minichromosome maintenance 2-7 complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data