anti-MCM2 Antibody

  • Catalog number
    28-535
  • Price
    Please ask
  • Size
    100 ug
  • Gene info
    The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
  • Gene names
    MCM2, BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibody is purified by protein A chromatography method.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Antigen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM2.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    MCM2 antibody can be used for detection of MCM2 by ELISA at 1:312500. MCM2 antibody can be used for detection of MCM2 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
  • Suspention pH azide
    Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
  • Keep at
    For short periods of storage (days) store at 4 grades C. For longer periods of storage, store MCM2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
  • Works with
    Human
  • Omim nr
    33356547
  • Ncbi nr
    NP_004517
  • KDa
    99 kDa
  • Vial with antibody
    Lyophilized
  • Quantity per ml
    1 mg/ml
  • NCBI GENE nr
    4171
  • GENE symbol
    MCM2
  • Antigene name
    minichromosome maintenance complex component 2
  • Source
    Homo sapiens
  • Protein nr
    P49736
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MCM2  
  • Gene symbol
    MCM7, MCM2
  • Short name
    anti-MCM2 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toMCM2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    minichromosome maintenance complex component 7
  • Synonyms gene
  • Synonyms gene name
    • minichromosome maintenance deficient (S. cerevisiae) 7
    • MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
  • Synonyms
  • Synonyms name
  • Locus
  • Discovery year
    1994-12-13
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • MCM family
    • MicroRNA protein coding host genes
    • minichromosome maintenance 2-7 complex
    • Protein phosphatase 1 regulatory subunits
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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