p38 MAPK (Phospho-Thr180/Tyr182) Antibody

• Catalog number
  bs-50486R
• Price
  Please ask
• Size
  0.1ml

• Long name
  p38 MAPK (Phospho-Thr180/Tyr182) Primary Polyclonal Antibody
• Also known as
  p38 MAPK (Phospho-Thr180/Tyr182) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  p38 MAPK (Phospho-Thr180/Tyr182)
• Specificity
  This is a highly specific antibody against p38 MAPK (Phospho-Thr180/Tyr182).
• Modification s
  Phosphorylation
• Modification site s
  Thr180/Tyr182
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Source
  Synthetic phospholyrated peptide (KLH coupled) corresponding to residues around Thr180/Tyr182 of human p38 MAP kinase
• Gene ID number
  1432
• Swiss Prot
  Q16539
• Tested Applications
  WB
• Recommended dilutions
  WB (1:5000)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation and other signals. p38 MAPK is relatively inactive in the non-phosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK, , , and , which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor-, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 and –6 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; MAPK14
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p38   MAPK   Phospho-Thr180/Tyr182  
• Short name
  Anti-p38 MAPK (Phospho-Thr180/Tyr182)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  p38 MAPK (Phospho-Thr180/Tyr182) Polyclonal Antibody
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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