RANK Receptor protein

• Catalog number
  30R-AR001
• Price
  Please ask
• Size
  100 µg

• Category
  Proteins
• Antibody Subtype
  Recombinant Proteins
• Area of research
  Cytokines & Growth Factors
• Reactivity
  Human
• Residues
  Region of RANK receptor protein corresponding to amino acids MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK.
• Type of protein
  Recombinant
• Expression System
  Escherichia coli
• Grade Purity
  Grater than 98% pure
• Form Buffer
  Lyophilized from 10 mM Na3PO4, pH 7.2. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
• Storage
  Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• Shipping conditions
  Blue Ice
• Tested for
  Please refer to the datasheet
• Bioactivity
  Determined by its ability to suppress the production of IFN-gamma from human PBMCs.
• URL
• More info
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  RANK   Receptor   protein  
• Gene symbol
  ANKFY1, TNFRSF11A
• Short name
  RANK Receptor protein
• Alternative name
  Purified recombinant Human RANK Receptor protein

Gene info

• Identity
  HGNC:20763
• Gene
  ANKFY1
• Long gene name
  ankyrin repeat and FYVE domain containing 1
• Synonyms
  • ANKHZN
  • KIAA1255
  • ZFYVE14
  • BTBD23
  • RANK-5
• Synonyms name
  • rabankyrin-5
• GenBank acession
  • AB033081
• Locus
  17p13.2
• Discovery year
  2003-04-29
• Entrez gene record
  51479
• Pubmed identfication
  • 10940552
  • 17273843
• RefSeq identity
  • NM_016376
• Classification
  • Zinc fingers FYVE-type
  • BTB domain containing
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000177727

Gene info

• Identity
  HGNC:11908
• Gene
  TNFRSF11A
• Long gene name
  TNF receptor superfamily member 11a
• Synonyms gene
  • PDB2
  • LOH18CR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 11a, activator of NFKB
  • Paget disease of bone 2
  • loss of heterozygosity, 18, chromosomal region 1
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Synonyms
  • RANK
  • CD265
  • FEO
  • ODFR
  • TRANCE-R
• Synonyms name
  • osteoclast differentiation factor receptor
  • receptor activator of nuclear factor kappa B
  • familial expansile osteolysis
  • TRANCE receptor
• GenBank acession
  • AF018253
• Locus
  18q21.33
• Discovery year
  1998-12-04
• Entrez gene record
  8792
• Pubmed identfication
  • 9367155
  • 10615125
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000132779
• Locus Specific Databases
  • LRG_194

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