Dihydrorhodamine 123

  • Catalog number
    D678953
  • Price
    Please ask
  • Size
    10 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
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  • Cas number
    109244-58-8
  • Chemical s molecular weight
    346.38
  • Chemical s main applications
    Dihydrorhodamine 123 (DHR 123) is a cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite. It is not fluorescent until oxidized by ROS to the highly fluorescent product Rhodamine 123. Neither NO, superoxide, nor hydrogen peroxide alone appear to oxidize DHR, rather, these ROS are thought to combine with other cellular components such as cytochrome c oxidase or Fe2+ in order to oxidize DHR 123 to its fluorescent derivative Rhodamine 123. Formation of Rhodamine 123 can be monitored by fluorescence spectroscopy using excitation and emission wavelengths of 500 and 536 nm, respectively, or by absorbance spectroscopy at 500 nm (ε = 78,800 M-1cm-1).
  • Other name
    D 23806; D 632; DHR;
  • Chemical s formula
    C21H18N2O3
  • Physical properties
    No Data Available
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    No Data Available
  • Stability conditions
    No Data Available
  • Storage
    No Data Available
  • Gene target
  • Short name
    Dihydrorhodamine 123
  • Alternative name
    Dihydrorhodamine 123
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