(R, S)-Niguldipine HCl, Ca2+ channel blocker

  • Catalog number
    SIH-319-10MG
  • Price
    Please ask
  • Size
    10 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    119934-51-9
  • Description
    Ca2+ channel blocker
  • Molecular weight
    646,18 g/mol
  • Primary research fields
    Neuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
  • Other name
    (R,S)-1,4-Dihydro-2,6-dimethyl-4-(3-n­itrophenyl)-3,5-pyridinedicarboxylic acid, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester hydrochloride
  • Product category
    Small Molecules
  • Product type
    Inhibitor
  • Chemical formula
    C36H39N3O6•HCl
  • Origin
    Synthetic
  • Purity pourcentage
    >98%
  • Soluble in
    Soluble to 10 mM in water
  • Physical appearance
    Yellow solid
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes
  • PubChem number
    Refer to PubChem
  • Scientific context
    Niguldipine is a calcium channel blocker and an a1-adrenergic receptor antagonist.
  • Bibliography
    1. Boer R., Grassegger A., Schudt C., Glossman H. (1999) Eur J Pharmacol. 172(2): 131-145. 2. Robinson J.P., Kendall D.A. (1990) Br J Pharmacol. 100(1): 3-4.
  • Release date
    8-Apr-2011
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of (R, S)-Niguldipine HCl (SIH-319), a L-type Ca channel blocker. CAS #: 113317-61-6. Molecular Formula: C36H39N3O6.HCl. Molecular Weight: 646.18 g/mol. Chemical structure of (R, S)-Niguldipine HCl, a L-type Ca channel blocker (SIH-319). CAS # 113317-61-6. Molecular Formula: C36H39N3O6.HCl.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.01
  • Gene target
    Niguldipine   HCl   Ca2   channel   blocker  
  • Short name
    (R, S)-Niguldipine HCl, Ca2+ channel blocker
  • Alternative name
    (R, S)-Niguldipine HCl, Ca2+ channel blocker
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