Rat Mouse CD8

Conjugation

Unconjugated
Note

For research use only.
Description

Cytotoxic T cells cluster differentiators for flow cytometry. This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus, Rattus norvegicus
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Identity

HGNC:1706
Gene

CD8A
Long gene name

CD8a molecule
Synonyms gene
- CD8
Synonyms gene name
- CD8 antigen, alpha polypeptide (p32)
- T-cell surface glycoprotein CD8 alpha chain
Locus

2p11.2
Discovery year

1986-01-01
Entrez gene record

925
Pubmed identfication
- 1541829
RefSeq identity
- NM_001768
Classification
- V-set domain containing
- CD molecules
VEGA ID

OTTHUMG00000130265
Locus Specific Databases
- CD8Abase: Mutation registry for CD8 deficiency
- LRG_44