anti-TNFRSF10A Antibody [32A1380]

  • Catalog number
    49-324
  • Price
    Please ask
  • Size
    0.05 mg
  • Gene info
    Cells undergo programmed cell death (Apoptosis) in response to various stimuli. Apoptosis is essential for morphogenesis, tissue homeostasis, and host defense Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL (3,4), which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.
  • Gene names
    TNFRSF10A, APO2, CD261, DR4, TRAIL-R1, TRAILR-1, TRAILR1, TRAIL receptor 1, CD261 antigen, Cytotoxic TRAIL receptor, Death receptor 4
  • Antibodie s label
    unlabelled serum
  • Purity
    Protein G Column
  • Ab raised in
    Mouse
  • Type
    Monoclonal
  • Monoclonal
    [32A1380  ]
  • Immunoglobulin
    IgG1
  • Antigen
    TNFRSF10A monoclonal antibody was made against a peptide corresponding to amino acid 1 to 20 of TNFRSF10A (Human).
  • Immuno application
    Western Blot, immuno-histo-chemistry, FLOW, NELISAut
  • Antibody advice
    TNFRSF10A antibody can be used in immunohistochemistry starting at 10 ug/mL.
  • Suspention pH azide
    PBS, 0.05% BSA, 0.05% sodium azide.
  • Keep at
    TNFRSF10A antibody can be stored short term 4 grades C. For long term storage aliquot and store at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
  • Works with
    Human
  • Omim nr
    313104273
  • Ncbi nr
    O00220
  • Vial with antibody
    in solution
  • NCBI GENE nr
    8797
  • GENE symbol
    TNFRSF10A
  • Antigene name
    tumor necrosis factor receptor superfamily, member 10a
  • Source
    Homo sapiens
  • Protein nr
    O00220
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    TNFRSF10A-DT, TNFRSF10A-AS1, TNFRSF10A
  • Short name
    anti-TNFRSF10A Antibody [32A1380]
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody totumor necrosis factor receptor superfamily, member 10a (antibody to-) [32A1380]
  • Alternative technique
    antibodies
  • Alternative to gene target
    tumor necrosis factor receptor superfamily, member 10a, APO2 and CD261 and DR4 and TRAILR-1 and TRAILR1, TNFRSF10A and IDBG-11715 and ENSG00000104689 and 8797, TRAIL binding, Plasma membranes
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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