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Immunogen
A phospho-specific peptide corresponding to residues surrounding Ser423 of human p70S6KB (AA420-426)
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Antibody s target
Human p70S6KB (pSer423)
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Antibody s full description
Rabbit Anti-Human p70S6KB (pSer423) Polyclonal
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Antibody s category
Polyclonal Antibodies
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Antibody s other name
70 kDa ribosomal protein S6 kinase 2 antibody, p70 beta antibody, p70 ribosomal S6 kinase beta antibody, p70 S6 kinase beta antibody, p70 S6K-beta antibody, p70 S6KB antibody, p70 S6Kbeta antibody, p70(S6K) beta antibody, p70-beta antibody, p70-S6K 2 antibody, P70S6K2 antibody, p70S6Kb antibody, Ribosomal protein S6 kinase 70kDa, polypeptide 2 antibody, Ribosomal protein S6 kinase beta 2 antibody, Rps6kb2 antibody, S6 kinase related kinase antibody, S6K beta 2 antibody, S6K-beta antibody, S6K-beta-2 antibody, S6K2 antibody, Serine/threonine protein kinase 14 beta antibody, Serine/threonine-protein kinase 14B antibody, SRK antibody, STK14B antibody
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Verified applications
WB, AM
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Raised in
Rabbit
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Antibody s reactivity
Human
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Antibody s recommended dilutions for use
WB (1:250); optimal dilutions for assays should be determined by the user.
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Antibody s purified from
Peptide Affinity Purified
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Recommended buffer for storage
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
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Antibody s concentration
See included datasheet or contact our support service
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Antibody s specificity
Detects 53.483 kDa.
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Storage recommendations
-20°C
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Shipping recommendations
Blue Ice or 4°C
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Certificate of analysis
A 1:250 dilution of SPC-1042 was sufficient for detection of p70S6KB (pSer423) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Antibody in cell
Cytoplasm, Nucleus
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Tissue specificity
See included datasheet or contact our support service.
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Scientific context
RPS6KB2 is a serine/theonine kinase. It phosphorylates ribosomal S6 protein and regulates protein synthesis and cell proliferation.
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Bibliography
Refer to PubMed
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Released date
29/Aug/2016
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NCBI number
NP_003943
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Gene number
6199
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Protein number
Q9UBS0
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Antibody s datasheet
Contact our support service to receive datasheet or other technical documentation.
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Representative figure link
No Data Available
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
1.4
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Net weight g
0.1
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Stock availabilit
In Stock
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Test
StressMark antibodies supplies antibodies that are for research of human proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus