RUNX3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-alpha-3, Core-binding Factor Subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2A3, PEBP2aC, PEBP2-alpha C, Polyomavirus Enhancer-binding Protein 2 alpha C Sub

  • Catalog number
    MBS609733
  • Price
    Please ask
  • Size
    100 Tests
  • Products_type
    Antibody
  • Products_short_name
    [RUNX3]
  • Products_name_syn
    [Anti -RUNX3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-alpha-3, Core-binding Factor Subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2A3, PEBP2aC, PEBP2-alpha C, Polyomavirus Enhancer-binding Protein 2 alpha C Sub]
  • Other_names
    [runt-related transcription factor 3 isoform 2; Runt-related transcription factor 3; runt-related transcription factor 3; CBF-alpha-3; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; oncogene AML-2; OTTHUMP00000003370; OTTHUMP00000003371; transcription factor AML2; acute myeloid leukemia gene 2; acute myeloid leukemia 2 protein; core-binding factor subunit alpha-3; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit; core-binding factor, runt domain, alpha subunit 3; polyomavirus enhancer-binding protein 2 alpha C subunit; runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEBP2-alpha C; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit]
  • Other_gene_names
    [RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3]
  • Clonality
    Monoclonal
  • Clone
    [10K25]
  • Reactivity
    Human
  • Specificity
    Recognizes human RUNX3.
  • Purity
    Affinity Purified Purified by Protein G affinity chromatography.
  • Form
    Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
  • Storage_stability
    May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
  • Tested_application
    Flow Cytometry (FC/FACS)
  • Description
    The RUNX3 (Runt- Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-alpha-3, Core-binding Factor Subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2A3, PEBP2aC, PEBP2-alpha C, Polyomavirus Enhancer-binding Protein 2 alpha C Sub is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene target
  • Gene symbol
    RUNX3, NFYC, NFYB, NFYA, RUNX3-AS1, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2
  • Short name
    RUNX3 (Runt- Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-alpha-3, Core-binding Factor Subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2A3, PEBP2aC, PEBP2-alpha C, Polyomavirus Enhancer-binding Protein 2 alpha C Sub
  • Host
    Mouse
  • Isotype
    IgG2A
  • Alternative name
    runt-related transcription factor 3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-a-3, Core-binding Factor functionnal sequence a-3, Oncogene AML-2, PEA2-a C, PEBP2A3, PEBP2aC, PEBP2-a C, Polyomavirus Enhancer-binding Protein 2 a C Sub
  • Alternative to gene target
    runt-related transcription factor 3, AML2 and CBFA3 and PEBP2aC, RUNX3 and IDBG-94257 and ENSG00000020633 and 864, ATP binding, nuclei, Runx3 and IDBG-196773 and ENSMUSG00000070691 and 12399, RUNX3 and IDBG-645327 and ENSBTAG00000019800 and 617389
  • Virus
    leukemia
Gene info
  • Identity
  • Gene
  • Long gene name
    RUNX family transcription factor 3
  • Synonyms gene
  • Synonyms gene name
    • runt-related transcription factor 3
    • runt related transcription factor 3
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1994-11-02
  • Entrez gene record
    864
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Runt-related transcription factors
    • MicroRNA protein coding host genes
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
  • Tree numbers
    • C04.557.337.372
    • C04.619.531
    • E05.598.500.496.500
  • Qualifiers
    diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery
Similar products
Filters
Contact
Chat with gentaur.com employee