Recombinant Human HGPRT/HPRT1 Protein(N-6His) 50µg

• Catalog number
  PKSH032542-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Hypoxanthine-Guanine Phosphoribosyltransferase; HGPRT; HGPRTase; HPRT1; HPRT
• Activity
  NA
• Sequence
  Met1-Ala218
• Fusion tag
  N-6His
• Accession
  P00492
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  27.8 kDa
• AP Mol Mass
  29 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM Tris, 250mM NaCl, 2mM EDTA, 30% Glycerol, pH 8.0.
• Reconstitution
  Please refer to it for detailed information.
• Background
  Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  HGPRT/HPRT1   Protein   N-6His   50µg  
• Gene symbol
  HPRT1
• Short name
  Recombinant HGPRT/HPRT1 Protein(N-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens HGPRT/hypoxanthine phosphoribosyltransferase 1 Protein(N-6His) 50µg
• Alternative technique
  rec
• Alternative to gene target
  hypoxanthine phosphoribosyltransferase 1, HGPRT and HPRT, HPRT1 and IDBG-86864 and ENSG00000165704 and 3251, guanine phosphoribosyltransferase activity, Cytoplasm, Hprt and IDBG-145409 and ENSMUSG00000025630 and 15452, LOC510369 and IDBG-640500 and ENSBTAG00000046220 and 510369

Gene info

• Identity
  HGNC:5157
• Gene
  HPRT1
• Long gene name
  hypoxanthine phosphoribosyltransferase 1
• Synonyms gene
  • HPRT
• Synonyms
  • HGPRT
• Synonyms name
  • Lesch-Nyhan syndrome
• GenBank acession
  • M26434
• Locus
  Xq26.2-q26.3
• Discovery year
  2001-06-22
• Entrez gene record
  3251
• Pubmed identfication
  • 12175903
• RefSeq identity
  • NM_000194
• VEGA ID
  OTTHUMG00000022452
• Locus Specific Databases
  • Hypoxanthine Guanine Phosphoribosyltransferase 1; Lech-Nyhan Syndrome

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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