Transglutaminase-2 Antibody

• Catalog number
  A1001-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Transglutaminase-2
• Target Alternative Name
  TGM2, Protein-glutamine gamma-glutamyltransferase 2, Tissue transglutaminase, TG, TGC, TGase C, Transglutaminase H, TGase H, TGase-2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse, Rat
• Immunogen Sequence
  human Transglutaminase-2 recombinant protein (Cat. No. 7700)
• Accession
  P21980
• Gene Id
  7052
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
• Purification
  Affinity purified rabbit IgG
• Application
  Western blot
• Positive Control
  Western blot
• Application And Usages
  Western blot: 1-4 µg/ml
• Description
  Tissue transglutaminase, a 78-kDa calcium dependent enzyme (EC 2.3.2.13), is found both in the intracellular and the extracellular spaces of various types of tissues. TG2 crosslinks proteins between the ε-amino group of a lysine residue and the γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). TG2 also possesses deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. Intracellular TG2 is thought to play an important role in apoptosis, while extracellular TG2 has been linked to cell adhesion, ECM stabilization, wound healing, receptor signaling, cellular proliferation, and cellular motility.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Transglutaminase-2  
• Gene symbol
  TGM2
• Short name
  Transglutaminase-2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  rabbit IgG
• Alternative name
  Transglutaminase-2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11778
• Gene
  TGM2
• Long gene name
  transglutaminase 2
• Synonyms gene name
  • transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
• Synonyms
  • TGC
• Synonyms name
  • C polypeptide, protein-glutamine-gamma-glutamyltransferase
• GenBank acession
  • M98478
• Locus
  20q11.23
• Discovery year
  1991-08-02
• Entrez gene record
  7052
• Pubmed identfication
  • 7912692
  • 11390390
• RefSeq identity
  • NM_198951
• Classification
  • Transglutaminases
• VEGA ID
  OTTHUMG00000032437

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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