TRAP-1 Antibody / HSP75

• Catalog number
  R32204
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRAP-1 / HSP75
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the TRAP1 antibody should be determined by the researcher.
• Intented use
  This TRAP1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q12931
• Purity
  Antigen affinity
• Description
  Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.
• Immunogen
  Amino acids 571-704 of human TRAP1 were used as the immunogen for the TRAP1 antibody.
• Storage
  After reconstitution, the TRAP1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRAP-1   HSP75  
• Gene symbol
  TRAP1, TGFBRAP1, ACP5, HSP90B2P, CD40LG, SCYL1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1
• Short name
  Anti-TRAP-1 / HSP75
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TRAP-1 / HSP75
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16264
• Gene
  TRAP1
• Long gene name
  TNF receptor associated protein 1
• Synonyms gene name
  • TNF receptor-associated protein 1
• Synonyms
  • HSP75
  • HSP90L
• GenBank acession
  • AF154108
• Locus
  16p13.3
• Discovery year
  2004-07-02
• Entrez gene record
  10131
• Pubmed identfication
  • 10652318
  • 7876093
• RefSeq identity
  • NM_016292
• Classification
  • Heat shock 90kDa proteins
• VEGA ID
  OTTHUMG00000129427

Gene info

• Identity
  HGNC:16836
• Gene
  TGFBRAP1
• Long gene name
  transforming growth factor beta receptor associated protein 1
• Synonyms gene name
  • transforming growth factor, beta receptor associated protein 1
• Synonyms
  • TRAP-1
  • TRAP1
  • VPS3
• Synonyms name
  • VPS3 CORVET complex subunit
• GenBank acession
  • AF022795
• Locus
  2q12.1-q12.2
• Discovery year
  2003-02-11
• Entrez gene record
  9392
• Pubmed identfication
  • 9545258
  • 11278302
  • 26463206
• RefSeq identity
  • NM_004257
• Classification
  • CORVET complex
• VEGA ID
  OTTHUMG00000130809

Gene info

• Identity
  HGNC:124
• Gene
  ACP5
• Long gene name
  acid phosphatase 5, tartrate resistant
• Synonyms
  • TRAP
  • HPAP
• Synonyms name
  • tartrate-resistant acid phosphatase
  • human purple acid phosphatase
• GenBank acession
  • X14618
• Locus
  19p13.2
• Discovery year
  1989-02-23
• Entrez gene record
  54
• Pubmed identfication
  • 8449511
  • 2338077
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000182036
• Locus Specific Databases
  • LRG_1218

Gene info

• Identity
  HGNC:12099
• Gene
  HSP90B2P
• Long gene name
  heat shock protein 90 beta family member 2, pseudogene
• Synonyms gene
  • TRAP1
  • TRA1P1
  • HSPCP2
• Synonyms gene name
  • tumor rejection antigen (gp96) pseudogene 1
  • tumor rejection antigen (gp96) 1 pseudogene 1
  • heat shock protein 90kDa beta (Grp94), member 2, pseudogene
• Synonyms
  • GRP94P1
  • GRP94b
• GenBank acession
  • AY956768
• Locus
  15q26.3
• Discovery year
  1991-07-10
• Entrez gene record
  7190
• Pubmed identfication
  • 16269234
• VEGA ID
  OTTHUMG00000171904

Gene info

• Identity
  HGNC:11935
• Gene
  CD40LG
• Long gene name
  CD40 ligand
• Synonyms gene
  • HIGM1
  • IMD3
  • TNFSF5
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
• Synonyms
  • CD40L
  • TRAP
  • gp39
  • hCD40L
  • CD154
• Synonyms name
  • CD40 antigen ligand
  • tumor necrosis factor (ligand) superfamily member 5
  • T-B cell-activating molecule
  • TNF-related activation protein
  • hyper-IgM syndrome
• GenBank acession
  • X67878
• Locus
  Xq26.3
• Discovery year
  1989-06-30
• Entrez gene record
  959
• Pubmed identfication
  • 1427881
  • 7678782
• RefSeq identity
  • NM_000074
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000022512
• Locus Specific Databases
  • CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome
  • Global Variome shared LOVD
  • LRG_141

Gene info

• Identity
  HGNC:14372
• Gene
  SCYL1
• Long gene name
  SCY1 like pseudokinase 1
• Synonyms gene
  • NTKL
• Synonyms gene name
  • N-terminal kinase-like
  • SCY1-like 1 (S. cerevisiae)
  • SCY1-like, kinase-like 1
• Synonyms
  • HT019
  • P105
  • GKLP
  • NKTL
  • TAPK
  • TRAP
  • TEIF
  • MGC78454
• Synonyms name
  • teratoma-associated tyrosine kinase
  • telomerase transcriptional elements-interacting factor
  • telomerase regulation-associated protein
• GenBank acession
  • AF225424
• Locus
  11q13.1
• Discovery year
  2001-01-16
• Entrez gene record
  57410
• Pubmed identfication
  • 11118629
• RefSeq identity
  • NM_020680
• Classification
  • Armadillo like helical domain containing
  • SCY1 like pseudokinases
• VEGA ID
  OTTHUMG00000166325

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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