anti-M-CSF Antibody

• Catalog number
  XP-5227Bt
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors.
• Gene names
  MCSF, CSF-1Macrophage colony-stimulating factor 1, Lanimostim, CSF-1
• Antibodie s label
  Biotin
• Purity
  Anti-hM-CSF specific antibody was purified by affinity chromatography and then biotinylated.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hM-CSF (human Granulocyte Colony Stimulating Factor).
• Immuno application
  ELISA, Western Blot
• Antibody advice
  ELISA:To detect hM-CSF by direct ELISA (using 100 μL/well antibody solution) this antibody can be used at a concentration of 0.15 - 0.30 ug/mL. Used in conjunction with compatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinant hM-CSF.Sandwich:To detect hM-CSF by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25 - 1.0 ug/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with our Polyclonal Anti-Human M-CSF (XP-5227) as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hM-CSF. Western Blot:To detect hM-CSF by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hM-CSF is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
• Keep at
  M-CSF antibody is stable for at least 2 years from date of receipt at -20 grades C. The reconstituted antibody is stable for at least two weeks at 2-8 grades C. Frozen aliquots are stable for at least 6 months when stored at -20 grades C. Avoid repeated freeze-thaw cycles.
• Works with
  Human
• Omim nr
  311033367
• Ncbi nr
  P09603
• Vial with antibody
  Lyophilized
• NCBI GENE nr
  1435
• GENE symbol
  CSF1
• Antigene name
  colony stimulating factor 1 (macrophage)
• Source
  Homo sapiens
• Protein nr
  P09603
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  M-CSF  
• Gene symbol
  CSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14, CSF3
• Short name
  anti-M-CSF Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toM-CSF (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2432
• Gene
  CSF1
• Long gene name
  colony stimulating factor 1
• Synonyms gene name
  • colony stimulating factor 1 (macrophage)
• Synonyms
  • M-CSF
  • MCSF
  • MGC31930
• Synonyms name
  • macrophage colony stimulating factor 1
• GenBank acession
  • BC021117
• Locus
  1p13.3
• Discovery year
  1986-01-01
• Entrez gene record
  1435
• Pubmed identfication
  • 1540160
• RefSeq identity
  • NM_000757
• VEGA ID
  OTTHUMG00000011646

Gene info

• Identity
  HGNC:2329
• Gene
  CPT1B
• Long gene name
  carnitine palmitoyltransferase 1B
• Synonyms gene name
  • carnitine palmitoyltransferase 1B (muscle)
• Synonyms
  • M-CPT1
  • CPT1-M
• Synonyms name
  • carnitine O-palmitoyltransferase 1B
• GenBank acession
  • U62733
• Locus
  22q13.33
• Discovery year
  1996-08-14
• Entrez gene record
  1375
• Pubmed identfication
  • 9070950
• RefSeq identity
  • NM_152246
• VEGA ID
  OTTHUMG00000137390

Gene info

• Identity
  HGNC:2434
• Gene
  CSF2
• Long gene name
  colony stimulating factor 2
• Synonyms gene name
  • colony stimulating factor 2 (granulocyte-macrophage)
• Synonyms
  • GM-CSF
  • GMCSF
• Synonyms name
  • sargramostim
  • molgramostim
  • granulocyte-macrophage colony stimulating factor
• GenBank acession
  • M11734
• Locus
  5q31.1
• Discovery year
  2001-06-22
• Entrez gene record
  1437
• Pubmed identfication
  • 3898082
  • 2999978
• RefSeq identity
  • NM_000758
• VEGA ID
  OTTHUMG00000059637

Gene info

• Identity
  HGNC:17020
• Gene
  IRAK3
• Long gene name
  interleukin 1 receptor associated kinase 3
• Synonyms gene name
  • interleukin-1 receptor-associated kinase 3
• Synonyms
  • IRAK-M
• GenBank acession
  • AF113136
• Locus
  12q14.3
• Discovery year
  2002-07-17
• Entrez gene record
  11213
• Pubmed identfication
  • 10383454
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169002

Gene info

• Identity
  HGNC:8889
• Gene
  PGAM2
• Long gene name
  phosphoglycerate mutase 2
• Synonyms gene name
  • phosphoglycerate mutase 2 (muscle)
• Synonyms
  • PGAM-M
• Locus
  7p13
• Discovery year
  1989-06-30
• Entrez gene record
  5224
• Classification
  • Phosphoglycerate mutases
  • Bisphosphoglycerate phosphatases
• VEGA ID
  OTTHUMG00000155355

Gene info

• Identity
  HGNC:20576
• Gene
  CYP20A1
• Long gene name
  cytochrome P450 family 20 subfamily A member 1
• Synonyms gene name
  • cytochrome P450, family 20, subfamily A, polypeptide 1
• Synonyms
  • CYP-M
• GenBank acession
  • AK021770
• Locus
  2q33.2
• Discovery year
  2003-03-20
• Entrez gene record
  57404
• RefSeq identity
  • NM_020674
• Classification
  • Cytochrome P450 family 20
• VEGA ID
  OTTHUMG00000132854

Gene info

• Identity
  HGNC:12614
• Gene
  USP16
• Long gene name
  ubiquitin specific peptidase 16
• Synonyms gene name
  • ubiquitin specific protease 16
• Synonyms
  • Ubp-M
• GenBank acession
  • AF126736
• Locus
  21q21
• Discovery year
  1999-07-09
• Pubmed identfication
  • 12838346
• Classification
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000078802

Gene info

• Identity
  HGNC:24374
• Gene
  CYB5B
• Long gene name
  cytochrome b5 type B
• Synonyms gene name
  • cytochrome b5 type B (outer mitochondrial membrane)
• Synonyms
  • CYB5-M
• Locus
  16q22.1
• Discovery year
  2006-01-30
• Entrez gene record
  80777
• Pubmed identfication
  • 11867265
  • 14733950
• RefSeq identity
  • NM_030579
• VEGA ID
  OTTHUMG00000133020

Gene info

• Identity
  HGNC:20503
• Gene
  H3C14
• Long gene name
  H3 clustered histone 14
• Synonyms gene
  • H3F2
  • H3FM
  • HIST2H3C
• Synonyms gene name
  • H3 histone family, member M
  • histone 2, H3c
  • histone cluster 2, H3c
  • histone cluster 2 H3 family member c
• Synonyms
  • MGC9629
  • H3/m
  • H3
  • H3.2
  • H3/M
• GenBank acession
  • AF531307
• Locus
  1q21.2
• Discovery year
  2003-02-19
• Entrez gene record
  126961
• Pubmed identfication
  • 12408966
  • 3013246
• RefSeq identity
  • NM_021059
• Classification
  • H3 histones
• VEGA ID
  OTTHUMG00000012190

Gene info

• Identity
  HGNC:2438
• Gene
  CSF3
• Long gene name
  colony stimulating factor 3
• Synonyms gene
  • GCSF
  • G-CSF
  • C17orf33
• Synonyms gene name
  • chromosome 17 open reading frame 33
  • colony stimulating factor 3 (granulocyte)
• Synonyms
  • MGC45931
• Synonyms name
  • granulocyte colony stimulating factor
  • pluripoietin
  • filgrastim
  • lenograstim
• Locus
  17q21.1
• Discovery year
  2001-06-22
• Entrez gene record
  1440
• Pubmed identfication
  • 3499671
  • 3501046
• RefSeq identity
  • NM_172220
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000133247

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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