VEGF-D, human recombinant
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Catalog number4643-1000
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PricePlease ask
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Size1 mg
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SynonymsVascular Endothelial Growth Factor-D, FIGF
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Alternative_namesVascular Endothelial Growth Factor-D, FIGF, c-Fos-induced growth factor
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DescriptionA protein involved in angiogenesis, lymphangiogenesis and endothelial cell growth and survival
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionLyophilized without additives
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Reconstitution InstructionsReconstitute in dH₂O to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
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Background InformationVEGF-D is most closely related to VEGF-C by virtue of the presence of N- and C-terminal extensions that are not found in other VEGF family members. In adult human tissues, VEGF-D mRNA is most abundant in heart, lung, skeletal muscle, colon, and small intestine. Analyses of VEGF-D receptor specificity revealed that VEGF-D is a ligand for both VEGF receptors (VEGFRs) VEGFR-2 (Flk1) and VEGFR-3 (Flt4) and can activate these receptors. However, VEGF-D does not bind to VEGFR-1. Expression of a truncated derivative of VEGF-D demonstrated that the receptor-binding capacities reside in the portion of the molecule that is most closely related in primary structure to other VEGF family members and that corresponds to the mature form of VEGF-C. In addition, VEGF-D is a mitogen for endothelial cells. Recombinant VEGF-D was expressed based on sequence from Genebank Accession# D89630, 20-354 aa.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolVEGFD, VEGFA, SNAR-D, VEGFC, DGCR11, LY6G6D, OR1L3, ULK4P2
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Short nameVEGF-D, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameVEGF-D, H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namevascular endothelial growth factor D
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Synonyms gene
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Synonyms gene name
- c-fos induced growth factor (vascular endothelial growth factor D)
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- VEGF family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namevascular endothelial growth factor A
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Synonyms gene
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Synonyms gene name
- vascular endothelial growth factor
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-01-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- VEGF family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesmall NF90 (ILF3) associated RNA D
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Synonyms gene name
- small ILF3/NF90-associated RNA D
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GenBank acession
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Locus
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Discovery year2008-07-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small NF90 (ILF3) associated RNAs
Gene info
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Identity
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Gene
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Long gene namevascular endothelial growth factor C
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-10-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- VEGF family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameDiGeorge syndrome critical region gene 11
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Synonyms gene name
- DiGeorge syndrome critical region gene 11
- DiGeorge syndrome critical region gene 11 (non-protein coding)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-11-13
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Entrez gene record
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Pubmed identfication
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphocyte antigen 6 family member G6D
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Synonyms gene
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Synonyms gene name
- chromosome 6 open reading frame 23
- lymphocyte antigen 6 complex, locus G6D
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Synonyms
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Locus
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Discovery year2002-04-05
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Entrez gene record
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Pubmed identfication
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Classification
- LY6/PLAUR domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 1 subfamily L member 3
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Synonyms gene name
- olfactory receptor, family 1, subfamily L, member 3
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Synonyms
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Locus
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Discovery year1999-12-09
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Entrez gene record
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Classification
- Olfactory receptors, family 1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameULK4 pseudogene 2
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Synonyms gene
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Synonyms gene name
- family with sequence similarity 7, member A2
- unc-51-like kinase 4 (C. elegans) pseudogene 2
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Synonyms
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Locus
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Discovery year2001-06-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
