Shh Antibody

• Catalog number
  bs-1544R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Shh Primary Polyclonal Antibody
• Also known as
  Shh PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Shh
• Specificity
  This is a highly specific antibody against Shh.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  20-70/462
• Subcellular location
  Cell membrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Shh
• Gene ID number
  6469
• Swiss Prot
  Q15465
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; Sonic hedgehog protein; SHH; HHG-1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Shh  
• Gene symbol
  SHH, SDCCAG8
• Short name
  Anti-Shh
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Shh Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  sonic hedgehog, HHG1 and HLP3 and HPE3 and MCOPCB5 and SMMCI and TPT and TPTPS, SHH and IDBG-50464 and ENSG00000164690 and 6469, laminin-1 binding, nuclei, Shh and IDBG-144309 and ENSMUSG00000002633 and 20423, SHH and IDBG-638249 and ENSBTAG00000024552 and

Gene info

• Identity
  HGNC:10848
• Gene
  SHH
• Long gene name
  sonic hedgehog signaling molecule
• Synonyms gene
  • HPE3
  • HLP3
• Synonyms gene name
  • sonic hedgehog (Drosophila) homolog
• Synonyms
  • HHG1
  • SMMCI
  • TPT
  • TPTPS
  • MCOPCB5
• Locus
  7q36.3
• Discovery year
  1995-03-10
• Entrez gene record
  6469
• Pubmed identfication
  • 7590746
• RefSeq identity
  • NM_000193
• Classification
  • Hedgehog signaling molecule family
• VEGA ID
  OTTHUMG00000151349

Gene info

• Identity
  HGNC:10671
• Gene
  SDCCAG8
• Long gene name
  SHH signaling and ciliogenesis regulator SDCCAG8
• Synonyms gene name
  • serologically defined colon cancer antigen 8
• Synonyms
  • NY-CO-8
  • CCCAP
  • SLSN7
  • NPHP10
  • BBS16
• Synonyms name
  • centrosomal colon cancer autoantigen protein
  • Bardet-Biedl syndrome 16
  • nephrocystin 10
  • Senior-Loken syndrome 7
• GenBank acession
  • AF039690
• Locus
  1q43-q44
• Discovery year
  1999-08-25
• Entrez gene record
  10806
• Pubmed identfication
  • 9610721
  • 20835237
  • 27224062
• RefSeq identity
  • NM_006642
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000039996

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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