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MERTK Antibody ALEXA FLUOR

MERTK Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-0548R-A350 | MERTK Antibody, ALEXA FLUOR 350 size: 100ul | 442.89 USD

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bs-0548R-A488 | MERTK Antibody, ALEXA FLUOR 488 size: 100ul | 442.89 USD

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bs-0548R-A555 | MERTK Antibody, ALEXA FLUOR 555 size: 100ul | 442.89 USD

Catalog number bs-0548R-A555
Price 442.89 USD
Size 100ul
Long name MERTK Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Also known as Anti-MERTK PAb ALEXA FLUOR 555
Conjugated with ALEXA FLUOR® 555
Excitation emission 553nm/568nm
Properties For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR 555
French translation anticorps
Label ALEXA FLUOR 555
Alternative name MERTK Polyclonal Antibody, ALEXA FLUOR 555
1. Gene info
Identity 7027
Gene MERTK
Long gene name MER proto-oncogene, tyrosine kinase
Synonyms gene name
  • c-mer proto-oncogene tyrosine kinase
Synonyms
  • mer
  • RP38
  • c-Eyk
  • Tyro12
GenBank acession
  • U08023
Locus 2q13
Discovery year 1998-11-30
Entrez gene record 10461
Pubmed identfication
  • 8086340
  • 10343112
Classification
  • Fibronectin type III domain containing
  • I-set domain containing
  • Receptor tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000131278
Locus Specific Databases
  • Mutations of the MER Receptor Tyrosine Kinase Gene
Product images
    #.png#bs#.jpgMERTK Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
Product files

bs-0548R-A594 | MERTK Antibody, ALEXA FLUOR 594 size: 100ul | 442.89 USD

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bs-0548R-A647 | MERTK Antibody, ALEXA FLUOR 647 size: 100ul | 442.89 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen MERTK
Specificity This is a highly specific antibody against MERTK.
Modification Unmodified
Modification Site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Immunogen range 530-580/994
Subcellular location Cytoplasm
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human of human MERTK
Gene ID Number 10461
Swiss Prot Q12866
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms MER; RP38; c-Eyk; c-mer; Tyro12; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; MERTK
Gene targetMERTK
Short name Anti-MERTK
Technique Antibody
Isotype Immunoglobulin G (IgG)
Alternative technique antibodies
Alternative to gene target c-mer proto-oncogene tyrosine kinase, c-mer and MER and RP38, MERTK and IDBG-66030 and ENSG00000153208 and 10461, transferase activity, Extracellular, Mertk and IDBG-205458 and ENSMUSG00000014361 and 17289, MERTK and IDBG-628865 and ENSBTAG00000005828 and 504429
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