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ABT 869 for cell activation

ABT 869 for cell activation is available 0 time from Biovision labs

Description ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC₅₀ value of 4 nM), but has much less activity (IC₅₀ values >1 µM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC₅₀ values of 2, 4 and 7 nM for PDGFRβ, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC₅₀ for human endothelial cells).
Peptide sequence N/A
CAS number 796967-16-3
Molecular weight 375.41
Category Biochemicals
Other name Linifanib
Molecular formula C₂₁H₁₈FN₅O
Physical appearance Crystalline solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥99%
Reconstitute instructions DMSO
Storage condition -20°C
Shipping condition RT
Maximum time for storage 24months
Storage instructions Protect from air and moisture
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetABT-869 for activation
Short name ABT-869 for activation
Technique activation
Alternative name ABT-869 to measure cellular activation
Tissue cell
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