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ABT 869 for cell activation

ABT 869 for cell activation is available 2 times from Biovision labs

1615-1 | ABT-869 for cell activation size: 1 mg | 241.67 USD

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1615-5 | ABT-869 for cell activation size: 5 mg | 698.91 USD

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Other name Linifanib
Supplied with N/A
Description ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC₅₀ value of 4 nM), but has much less activity (IC₅₀ values >1 µM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC₅₀ values of 2, 4 and 7 nM for PDGFRβ, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC₅₀ for human endothelial cells).
Category Biochemicals
Molecular formula C₂₁H₁₈FN₅O
Is it cell-permeable? Yes
Molecular weight 375.41
Storage condition -20°C
Shipping condition RT
Purification ≥99%
Peptide sequence N/A
Is this a salt? No
CAS number 796967-16-3
Storage instructions Protect from air and moisture
Maximum time for storage 24months
Physical appearance Crystalline solid
Reconstitute instructions DMSO
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetABT-869 for activation
Short name ABT-869 for activation
Technique activation
Alternative name ABT-869 to measure cellular activation
Tissue cell
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