Ruxolitinib, Free base
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Catalog number2139-100
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PricePlease ask
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Size100 mg
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Alternative_nameINCB018424; INC18424; NCB018424; NCB18424
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DescriptionRuxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC₅₀'s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis.
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CAS Number941678-49-5
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Structure AvailableYes
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Molecular FormulaC₁₇H₁₈N₆
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Molecular Weight306.37
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Cell PermeableYes
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Purity≥99% by HPLC
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SolubilitiesDMSO (25 mg/ml) or EtOH (~ 15 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent JAK inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD12031592
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PubChem CID25126798
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SMILESC1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
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InChiInChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
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InChi KeyHFNKQEVNSGCOJV-OAHLLOKOSA-N
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MSDS AvailableYes
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Gene target
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Short nameRuxolitinib, Free base
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Alternative nameRuxolitinib, Free base
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