Ruxolitinib, Free base

  • Catalog number
    2139-100
  • Price
    Please ask
  • Size
    100 mg
  • Alternative_name
    INCB018424; INC18424; NCB018424; NCB18424
  • Description
    Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC₅₀'s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis.
  • CAS Number
    941678-49-5
  • Structure Available
    Yes
  • Molecular Formula
    C₁₇H₁₈N₆
  • Molecular Weight
    306.37
  • Cell Permeable
    Yes
  • Purity
    ≥99% by HPLC
  • Solubilities
    DMSO (25 mg/ml) or EtOH (~ 15 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent JAK inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD12031592
  • PubChem CID
    25126798
  • SMILES
    C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
  • InChi
    InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
  • InChi Key
    HFNKQEVNSGCOJV-OAHLLOKOSA-N
  • MSDS Available
    Yes
  • Gene target
    Ruxolitinib   Free   base  
  • Short name
    Ruxolitinib, Free base
  • Alternative name
    Ruxolitinib, Free base
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